Title:
CHEMICAL COMPOUND
Document Type and Number:
Japanese Patent JP2013139459
Kind Code:
A
Abstract:
To provide compounds capable of being used as inhibitors or modulators of PIM-1 and/or PIM-2, and/or PIM-3 protein kinase activity or enzyme function, and to provide pharmaceutical compositions comprising the compounds and capable of being used in the prevention and treatment of PIM kinase-related conditions and diseases, preferably cancer.
This invention relates to compounds represented by the following general formula.
More Like This:
| WO/2003/009807 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS |
| JPS63243079 | THIAZOLE DERIVATIVE |
Inventors:
DAKIN LESLIE
DOWLING JAMES EDWARD
LAMB MICHELLE
READ JON
SU QIBIN
ZHENG XIAOLAN
DOWLING JAMES EDWARD
LAMB MICHELLE
READ JON
SU QIBIN
ZHENG XIAOLAN
Application Number:
JP2013031176A
Publication Date:
July 18, 2013
Filing Date:
February 20, 2013
Export Citation:
Assignee:
ASTRAZENECA AB
International Classes:
C07D277/20; A61K31/427; A61K31/437; A61K31/454; A61K31/4709; A61K31/496; A61K31/5377; A61K31/541; A61K31/551; A61P35/00; A61P35/02; A61P43/00; C07D277/34; C07D417/10; C07D417/12; C07D417/14; C07D471/04
Domestic Patent References:
| JPH093067A | 1997-01-07 | |||
| JP2006523724A | 2006-10-19 | |||
| JP3850450B2 | 2006-11-29 | |||
| JP5261575B2 | 2013-08-14 |
Foreign References:
| WO2004093809A2 | 2004-11-04 | |||
| US20020120144A1 | 2002-08-29 | |||
| WO2009064486A2 | 2009-05-22 | |||
| WO2006069186A2 | 2006-06-29 | |||
| WO2001034133A2 | 2001-05-17 | |||
| EP0976748A1 | 2000-02-02 |
Other References:
JPN6013015127; Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｌｅｔｔｅｒｓ Ｖｏｌ．１５， Ｎｏ．１７, 20050901, ｐ．３９３０-３９３３
JPN6013015129; Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．５２， Ｎｏ．１, 20090109, ｐ．７４-８６
JPN6013015131; Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｌｅｔｔｅｒｓ Ｖｏｌ．２２, 20120606, Ｐ．４５９９-４６０４
JPN5011006476; ＯＴＴＡＮＡ Ｒ: 'ＩＮ ＶＩＴＲＯ ＡＮＴＩＰＲＯＬＩＦＥＲＡＴＩＶＥ ＡＣＴＩＶＩＴＹ ＡＧＡＩＮＳＴ ＨＵＭＡＮ ＣＯＬＯＮ ＣＡＮＣＥＲ ＣＥＬＬ ＬＩＮＥＳ 以下備考' ＢＩＯＯＲＧＡＮＩＣ ＆ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ ＬＥＴＴＥＲＳ Ｖ１５ Ｎ１７, 20050901, Ｐ３９３０-３９３３, ＰＥＲＧＡＭＯＮ， ＥＬＳＥＶＩＥＲ ＳＣＩＥＮＣＥ
JPN5011006477; ＸＩＡ ＺＵＰＩＮＧ: 'ＳＹＮＴＨＥＳＩＳ ＡＮＤ ＥＶＡＬＵＡＴＩＯＮ ＯＦ ＮＯＶＥＬ ＩＮＨＩＢＩＴＯＲＳ ＯＦ ＰＩＭ-１ ＡＮＤ ＰＩＭ-２ ＰＲＯＴＥＩＮ ＫＩＮＡＳＥＳ' ＪＯＵＲＮＡＬ ＯＦ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ Ｖ５２ Ｎ１, 20090108, Ｐ７４-８６
JPN6013015129; Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．５２， Ｎｏ．１, 20090109, ｐ．７４-８６
JPN6013015131; Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｌｅｔｔｅｒｓ Ｖｏｌ．２２, 20120606, Ｐ．４５９９-４６０４
JPN5011006476; ＯＴＴＡＮＡ Ｒ: 'ＩＮ ＶＩＴＲＯ ＡＮＴＩＰＲＯＬＩＦＥＲＡＴＩＶＥ ＡＣＴＩＶＩＴＹ ＡＧＡＩＮＳＴ ＨＵＭＡＮ ＣＯＬＯＮ ＣＡＮＣＥＲ ＣＥＬＬ ＬＩＮＥＳ 以下備考' ＢＩＯＯＲＧＡＮＩＣ ＆ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ ＬＥＴＴＥＲＳ Ｖ１５ Ｎ１７, 20050901, Ｐ３９３０-３９３３, ＰＥＲＧＡＭＯＮ， ＥＬＳＥＶＩＥＲ ＳＣＩＥＮＣＥ
JPN5011006477; ＸＩＡ ＺＵＰＩＮＧ: 'ＳＹＮＴＨＥＳＩＳ ＡＮＤ ＥＶＡＬＵＡＴＩＯＮ ＯＦ ＮＯＶＥＬ ＩＮＨＩＢＩＴＯＲＳ ＯＦ ＰＩＭ-１ ＡＮＤ ＰＩＭ-２ ＰＲＯＴＥＩＮ ＫＩＮＡＳＥＳ' ＪＯＵＲＮＡＬ ＯＦ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ Ｖ５２ Ｎ１, 20090108, Ｐ７４-８６
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Takumi Terachi
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Takumi Terachi
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