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Title:
COMPOSITE OF CATIONIC POLYSACCHARIDE AND MAGNETIC PARTICLE
Document Type and Number:
Japanese Patent JP2010030915
Kind Code:
A
Abstract:

To provide an MRI contrast medium stable in a culture solution and enabling unerring MRI diagnosis.

The composite of a cationic polysaccharide derivative and a magnetic metal oxide has the following properties: the aggregation degree is 4.0 times when the composite stands still in D-MEM (Dulbecco's Modified Eagle Medium) containing 20% fetal bovine serum at 37C under 5% CO2 condition for 24hr.


Inventors:
SAITO HIROAKI
MURASE KATSUTOSHI
UCHIDA HISAAKI
HAYASHI SHUJI
NOGUCHI HIROFUMI
Application Number:
JP2008192195A
Publication Date:
February 12, 2010
Filing Date:
July 25, 2008
Export Citation:
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Assignee:
MEITO SANGYO KK
UNIV NAGOYA
International Classes:
A61K49/00
Domestic Patent References:
JP2007112904A2007-05-10
JP2921984B21999-07-19
Foreign References:
WO2007097473A12007-08-30
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Tsutomu Toyama