Title:
含ケイ素置換基を導入した化合物、並びにそれを含む一重項酸素発生剤及び癌治療薬
Document Type and Number:
Japanese Patent JP5843113
Kind Code:
B2
Abstract:
A compound represented by any of general formulae (I) to (IV) is to be used as the active ingredient of a singlet oxygen-generating agent. In each of R1 to R20 in general formula (I), R1 to R24 in general formula (II), R1 to R28 in general formula (III) and R1 to R16 in general formula (IV), at least one is a member selected from substituents represented by general formula (i) and (ii) [in general formulae (i) and (ii), Ra, Rb and Rc independently represent a substituent selected from among hydrogen, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, t-butyl, phenyl, methoxy, ethoxy and trimethylsilyl; and n is 1 or greater], and at least one is a substituent represented by general formula (a) [in general formula (a), Ra and Rb independently represent a substituent selected from among hydrogen, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, t-butyl, phenyl, methoxy, ethoxy and trimethylsilyl; and m is 0 or greater].
Inventors:
Hiroaki Horiuchi
Hosaka Masahiro
Hiroshi Hiratsuka
Toshiyuki Takeuchi
Kushin Soichiro
Shintaro Ishida
Hosaka Masahiro
Hiroshi Hiratsuka
Toshiyuki Takeuchi
Kushin Soichiro
Shintaro Ishida
Application Number:
JP2012531819A
Publication Date:
January 13, 2016
Filing Date:
August 24, 2011
Export Citation:
Assignee:
Gunma University
International Classes:
C07F7/10; A61K31/695; A61P35/00
Domestic Patent References:
| JP2009280702A | 2009-12-03 | |||
| JP2008274082A | 2008-11-13 | |||
| JP2007055978A | 2007-03-08 |
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Shinichi Sanuki
Shinichi Sanuki