PURPOSE: To produce tyrosine, etc., in high efficiency, by culturing a coryne-type bacterial cell having a recombinant DNA in which a gene coding shikimic acid kinase is connected to a plasmid vector proliferative in a coryne-type bacterial cell.
CONSTITUTION: A coryne-type bacterial cell containing a recombinant DNA in which a gene manifesting in a coryne-type bacterial cell and coding shikimic acid kinase is connected to a plasmid vector proliferative in coryne-type bacterial cell is prepared beforehand. Cultivation of the bacterial strain gives tyrosine and/or phenylalanine. It is preferable to insert a prephenic acid dehydratase gene, prephenic acid transaminase, etc., in addition to shikimic acid kinase gene in the case of producing a phenylalanine or tyrosine-producing strain.
ITO HISAO
MATSUI KAZUHIKO
SANO TAKANOSUKE
EI HITOSHI
JPS6024192A | 1985-02-06 | |||
JPS6034197A | 1985-02-21 | |||
JPS6066984A | 1985-04-17 |
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