Title:
DERIVATIVES OF N2-(3-PYRIDYL OR PHENYL)-N4-(4-PIPERIDYL)-2,4-PYRIMIDINEDIAMINE USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES, AUTOIMMUNE OR PROLIFERATIVE DISEASES
Document Type and Number:
Japanese Patent JP2015110629
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide compounds which are useful as inhibitors of protein kinase C (PKC) and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC.SOLUTION: This disclosure relates to derivatives of N2-(3-pyridine or phenyl)N4-(4-piperidyl)-2,4-pyrimidinediamine, represented by formula (I), or salt or stereoisomer thereof, where Q is substituted/unsubstituted C or N.
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Inventors:
RAJINDER SINGH
LI HUI
ZHAO HAORAN
RAO KOLLURI
TSO KIN
JOHN RAMPHAL
GU SHIHAI
CARLOS VALDEZ
ZHANG JING
EMILY STAUFFER
MATTHEW DUNCTON
SALVADOR ALVAREZ
LI HUI
ZHAO HAORAN
RAO KOLLURI
TSO KIN
JOHN RAMPHAL
GU SHIHAI
CARLOS VALDEZ
ZHANG JING
EMILY STAUFFER
MATTHEW DUNCTON
SALVADOR ALVAREZ
Application Number:
JP2015018931A
Publication Date:
June 18, 2015
Filing Date:
February 03, 2015
Export Citation:
Assignee:
RIGEL PHARMACEUTICALS INC
International Classes:
C07D401/12; A61K31/538; A61P1/04; C07D401/14; C07D405/14; C07D409/14; C07D413/14
Attorney, Agent or Firm:
Naoto Uchida