Title:
【発明の名称】核レセプターのリガンドおよびリガンド結合ドメイン
Document Type and Number:
Japanese Patent JP2001524489
Kind Code:
A
Abstract:
The present invention provides new methods, particularly computational methods, and compositions for the generation of nuclear receptor synthetic ligands based on the three dimensional structure of nuclear receptors, particularly the thyroid receptor (herein referred to as "TR"). Also provided are crystals, nuclear receptor synthetic ligands, and related methods.
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Inventors:
Scanlan, Thomas S.
Baxter, John Dee.
Fleterick, Robert Jay.
Wagner, Richard Elle.
Kushner, Peter Jay.
April Letty, James W.
West, Brian El.
Shaw, Andrew K.
Baxter, John Dee.
Fleterick, Robert Jay.
Wagner, Richard Elle.
Kushner, Peter Jay.
April Letty, James W.
West, Brian El.
Shaw, Andrew K.
Application Number:
JP2000522122A
Publication Date:
December 04, 2001
Filing Date:
November 25, 1998
Export Citation:
Assignee:
The Regents of the University of California
International Classes:
G01N33/50; A61K31/192; A61K31/196; A61K31/198; A61K31/27; A61P43/00; C07K1/00; C07K14/00; C07K14/72; G01N33/15; G01N33/78; G16B15/30; (IPC1-7): A61K31/192; A61K31/196; A61K31/198; A61P43/00; C07K14/00; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Takashi Ishida (4 others)