Title:
DICATION COMPOUND SELECTIVELY RECOGNIZING G-QUADRUPLE CHAIN DNA
Document Type and Number:
Japanese Patent JP2007153875
Kind Code:
A
Abstract:
To provide a highly selective dication compound for connecting G-quadruple chain DNA.
Some compounds indicate groove connection against G-quadruple chain DNA and in vitro and in vivo activities against Trypanosoma brucei rhodesiense. These compounds correspond to new medicines for treating cancers, malaria, leishmaniasis and trypanosomiasis.
Inventors:
TIDWELL RICHARD R
BOYKIN DAVID W
ISMAIL MOHAMED A
WILSON W DAVID
WHITE ELIZABETH W
KUMAR ARVIND
NANJUNDA RUPESH
BOYKIN DAVID W
ISMAIL MOHAMED A
WILSON W DAVID
WHITE ELIZABETH W
KUMAR ARVIND
NANJUNDA RUPESH
Application Number:
JP2006297701A
Publication Date:
June 21, 2007
Filing Date:
November 01, 2006
Export Citation:
Assignee:
UNIV NORTH CAROLINA CHAPEL HILL
GEORGIA STATE UNIV RES FOUNDAT
GEORGIA STATE UNIV RES FOUNDAT
International Classes:
A61K31/33; A61K31/34; A61K31/381; A61K31/4178; A61K31/4184; A61K31/443; A61K31/4436; A61K31/444; A61K45/00; A61P31/04; A61P31/10; A61P31/12; A61P33/02; A61P35/00; A61P43/00; C07D307/56; C07D333/24; C07D405/14; C07D409/14; C07D421/04; C07D421/14; C12N15/00
Attorney, Agent or Firm:
Toru Ishikawa
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