Title:
(ハイドロ)フルオロカーボン溶剤におけるラセミ化合物の動的速度論的分割(DKR)方法
Document Type and Number:
Japanese Patent JP2009533067
Kind Code:
A
Abstract:
A process for preparing a third compound stereo-selectively which process comprises reacting a substrate comprising a first enantiomeric compound with a racemisation catalyst to give a second enantiomeric compound, and concurrently reacting the second enantiomeric compound in the presence of a biological catalyst to give the third compound, wherein the process is performed in a solvent comprising at least one (hydro) fluorocarbon. The biological catalyst is preferably an enzyme. The substrate preferably comprises a racemate of the first and second enantiomeric compounds. The second enantiomeric compound may be reacted with a reagent, such as acyl donor, to form the third compound in the presence of the biological catalyst.
Inventors:
Jason, Micklefield
Anthony, John, Ball
Stuart, Core
Anthony, John, Ball
Stuart, Core
Application Number:
JP2009505954A
Publication Date:
September 17, 2009
Filing Date:
April 19, 2007
Export Citation:
Assignee:
INEOS FLUOR HOLDINGS LIMITED
International Classes:
C12P41/00; C07B55/00; C07B61/00; C07C29/56; C07C33/20; C07C33/22; C07C67/03; C07C69/157; C07C209/68; C07C211/27
Foreign References:
| US6201151B1 | 2001-03-13 | |||
| WO2004083444A1 | 2004-09-30 |
Attorney, Agent or Firm:
Kenji Yoshitake
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Masaharu Takamura
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Masaharu Takamura