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Title:
FINE SPHERE IN CONTRAST AGENT
Document Type and Number:
Japanese Patent JP2006045238
Kind Code:
A
Abstract:

To provide an uncrosslinked fine sphere useful for producing a contrast agent comprising a fine sphere containing a gas of sulfur hexafluoride or a low molecular weight fluorinated hydrocarbon encapsulated in a protein shell, the protein being crosslinked by using a crosslinking group having a biodegradable bond and which is used in diagnostic ultrasound examination.

The fine sphere comprising sulfur hexafluoride or the low molecular weight fluorinated hydrocarbon encapsulated in the protein shell is produced.


Inventors:
KLAVENESS JO
RONGVED PAL
STRANDE PER
Application Number:
JP2005250437A
Publication Date:
February 16, 2006
Filing Date:
August 31, 2005
Export Citation:
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Assignee:
AMERSHAM HEALTH AS
International Classes:
A61K49/00; A61B8/00; A61K9/50; A61K47/26; A61K47/42; A61K49/04; A61K49/22; C07C69/96
Attorney, Agent or Firm:
Chika Takagi
Kosuke Nishimura