Title:
真菌抗原及びその製造方法
Document Type and Number:
Japanese Patent JP4118340
Kind Code:
B2
Abstract:
There can be provided a fungal antigen which is an insoluble fraction obtainable from fungal cells of which cell wall has been substantially removed or at least partially removed; a process for producing the same; a nucleic acid encoding the fungal antigen; a biologic product containing the fungal antigen; a method of stimulating immunological responses by using the biologic product; a method of suppressing allergic reaction to fungi in a vertebrate; and a method for diagnosing a disease caused by fungi in a vertebrate.
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Inventors:
Takesako
Mizutani Shigeru
Endo Masahiro
Ikunoshin Kato
Mizutani Shigeru
Endo Masahiro
Ikunoshin Kato
Application Number:
JP51202798A
Publication Date:
July 16, 2008
Filing Date:
August 29, 1997
Export Citation:
Assignee:
Takara Bio Inc.
International Classes:
C07K14/37; G01N33/53; A61K39/00; A61K39/35; A61P31/10; A61P37/00; A61P37/04; A61P37/08; C07K14/40; C12N15/09; C12N15/31; G01N33/569; C12R1/725
Foreign References:
| US5275814 |
Other References:
VENEZIA,R.A. et al., ”Efficacy of the Candida Precipitin Test”, Am.J.Clin.Pathol., 1974年, Vol.61, No.6, pp.849-855
NAVARRO,D. et al., ”Diagnosis of Systemic Candidiasis by Enzyme Immunoassay Detection of Specific Antibodies to Mycelial Phase Cell Wall and Cytoplasmic Candidal Antigens”, Eur.J.Clin.Microbiol.Infect.Dis., 1993年,Vol.12,No.11,pp.839-846
HEARN,V.M. et al., ”The Preparation and Chemical Composition of Fractions from Aspergillus fumigatus Wall and Protoplast Possesing Antigenic Activity”, J.General Miclobiology, 1979年, Vol.112, pp.35-44
CRAMERI, R. et al., ”Humoral and Cell-mediated Autoimmunity in Allergy to Aspergillus fumigatus”, J. Exp. Med., 1996年 7月, Vol.184, pp.265-270
HAMILTON, A.J. et al., J. Clin. Microbiol., 1995年, Vol.33, No.2,pp.495-496
NAVARRO,D. et al., ”Diagnosis of Systemic Candidiasis by Enzyme Immunoassay Detection of Specific Antibodies to Mycelial Phase Cell Wall and Cytoplasmic Candidal Antigens”, Eur.J.Clin.Microbiol.Infect.Dis., 1993年,Vol.12,No.11,pp.839-846
HEARN,V.M. et al., ”The Preparation and Chemical Composition of Fractions from Aspergillus fumigatus Wall and Protoplast Possesing Antigenic Activity”, J.General Miclobiology, 1979年, Vol.112, pp.35-44
CRAMERI, R. et al., ”Humoral and Cell-mediated Autoimmunity in Allergy to Aspergillus fumigatus”, J. Exp. Med., 1996年 7月, Vol.184, pp.265-270
HAMILTON, A.J. et al., J. Clin. Microbiol., 1995年, Vol.33, No.2,pp.495-496
Attorney, Agent or Firm:
Yoshinori Hosoda