GASTROINTESTINAL TRACT ABSORPTION TYPE PROLONGED NITROGLYCERIN PREPARATION AND USE THEREOF

Title:

GASTROINTESTINAL TRACT ABSORPTION TYPE PROLONGED NITROGLYCERIN PREPARATION AND USE THEREOF

Document Type and Number:

Japanese Patent JPH07258078

Kind Code:

A

Abstract:

PURPOSE: To obtain the preparation useful not only for angina pectoris but also spastic anemia, etc., having excellent absorption from a gastrointestinal tract and stable and durable action, comprising a carrier containing hydroxypropyl cellulose and pullulan.

CONSTITUTION: This gastrointestinal tract absorption type duct nitroglycerin preparation comprises (A) a carrier for a preparation contains (B) lactose, (C) hydroxypropyl cellulose and (D) pullulan. The blended amount of nitroglycerin is an amount smaller than 10wt.%. The component A has a particle size distribution of about 60 mesh. The blended amounts are 5-70-wt.% of the component B, 10-80wt.% of the component C and 10-80wt.% of the component D. The viscosity of the component C in 2wt.% aqueous resistance at 20°C is preferably adjusted to 3.0-4,000cp, preferably 150-4,000cp.

Inventors:

SAWAI KIICHI
MITANI TAKAHIKO
NINOMIYA NAOHISA
TSURUMI YOSHIMI

Application Number:

JP5567094A

Publication Date:

October 09, 1995

Filing Date:

March 25, 1994

Export Citation:

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Assignee:

SANWA KAGAKU KENKYUSHO CO

International Classes:

A61K9/22; A61K31/21; A61K47/26; A61K47/36; A61K47/38; A61P9/08; A61P37/06; A61P43/00; (IPC1-7): A61K31/21; A61K9/22; A61K31/21; A61K47/26; A61K47/36; A61K47/38

Attorney, Agent or Firm:

Isao Sasaki (1 person outside)

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