Title:
HUMANIZED ANTI CD-11a ANTIBODIES
Document Type and Number:
Japanese Patent JP2006036779
Kind Code:
A
Abstract:
To provide various uses of humanized anti-CD11a antibodies.
Humanized anti-CD11a antibodies and various uses therefor are disclosed. The humanized anti-CD11a antibody may bind specifically to human CD11a I-domain, have an IC50(nM) value of no more than about 1nM for preventing adhesion of Jurkat cells to normal human epidermal keratinocytes expressing ICAM-1, and/or an IC50 (nM) value of no more than about 1nM in the mixed lymphocyte response assay.
More Like This:
| WO/2002/096951 | MOLECULES FOR DISEASE DETECTION AND TREATMENT |
| JPS63313596 | PRODUCTION OF ANTIBODY AGAINST CANCER GENE ANTIGEN |
Inventors:
JARDIEU PAULA M
PRESTA LEONARD G
PRESTA LEONARD G
Application Number:
JP2005224609A
Publication Date:
February 09, 2006
Filing Date:
August 02, 2005
Export Citation:
Assignee:
GENENTECH INC
International Classes:
A61K39/395; G01N33/53; A61P1/00; A61P1/04; A61P11/06; A61P17/06; A61P25/00; A61P29/00; A61P37/06; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/08; A61K38/00
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro
Previous Patent: MULTI-PROCESS METHOD FOR CONTINUOUSLY PRODUCING ALICYCLIC DIISOCYANATE
Next Patent: METHOD FOR PRODUCING RUTHENIUM COMPLEX
Next Patent: METHOD FOR PRODUCING RUTHENIUM COMPLEX