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Title:
HOST CELL FOR PRODUCING PROTEIN OF INTEREST
Document Type and Number:
Japanese Patent JP2023156329
Kind Code:
A
Abstract:
To provide host cells which are modified to reduce HCP impurities when producing a recombinant or heterologous protein.SOLUTION: A eukaryotic host cell is engineered to produce a heterologous protein of interest (POI), where the cell is genetically modified to reduce the production of at least one of three different endogenous host cell proteins (HCPs).SELECTED DRAWING: None

Inventors:
KATRIEN CLAES
JAMES GRAHAM
SYLWIA JOZWIAK
CHRISTOPH KIZIAK
Application Number:
JP2023118841A
Publication Date:
October 24, 2023
Filing Date:
July 21, 2023
Export Citation:
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Assignee:
LONZA AG
International Classes:
C12N1/19; C12N1/15; C12N1/21; C12N5/10
Attorney, Agent or Firm:
Patent Attorney Corporation Suzue Patent General Office