Title:
【発明の名称】電解的経皮投与のための組成物及びそのための経皮パッチ
Document Type and Number:
Japanese Patent JP2670794
Kind Code:
B2
Abstract:
A chemical composition for electrolytic transdermal transport of a protein to the blood stream of the patient comprises: a) a protein, b) a cosolvent with negative Setschenow constants, and c) water. Some of the preferred proteins are: insulin, protamine sulfate, calcitonin, glucagon, and corticotropin. Some of the preferred dissociating agents with negative Setschenow constants are: urea, propylurea, potassium iodide, sodium perchlorate, and guanidine hydrochloride. The electrolytic device (10) containing the composition to be transdermally delivered comprises: two electrode elements (22, 36) separated by barrier means (34), a reservoir (24) containing the composition of the invention, an electronic/electrolytic circuit including a source of a power (28), a cover (12), and adhesive (36) means holding the device to the patient's skin (18). A semipermeable membrane (22) between the patient's skin and the electrolytic device is optional.
More Like This:
| WO/2016/038059 | PARENTERAL COMPOSITIONS AND USES THEREOF |
| WO/1997/033531 | ORAL PEPTIDE PHARMACEUTICAL PRODUCTS |
| JPH06501029 | 【発明の名称】生体活性組成物 |
Inventors:
Dan Sivalis
Sanford Rosen
Sanford Rosen
Application Number:
JP2861788A
Publication Date:
October 29, 1997
Filing Date:
February 09, 1988
Export Citation:
Assignee:
Drug Delivery Systems Incorporated
International Classes:
A61K9/00; A61K9/08; A61K38/00; A61K38/16; A61K38/26; A61K38/28; A61M37/00; A61N1/30; (IPC1-7): A61K9/08; A61K38/00; A61K38/16; A61K38/26; A61K38/28; A61M37/00
Domestic Patent References:
| JP59118167A | ||||
| JP61259679A |
Attorney, Agent or Firm:
Murao Mikio