Title:
IMIDAZOLOTHIAZOLE COMPOUND FOR TREATING DISEASE
Document Type and Number:
Japanese Patent JP2011037858
Kind Code:
A
Abstract:
To provide a pharmaceutical composition for treating proliferative disease, which is a modulator relating to activity of an enzyme such as a kinase and is useful to treat, prevent or improve disease, affection or one or more symptoms thereof, relating to the activity of the enzyme.
A compound for adjusting the activity of a receptor kinase and for treating, preventing or improving disease, affection or one or more symptoms between which the receptor kinase lies, is provided.
Inventors:
BHAGWAT SHRIPAD
CHAO QI
GROTZFELD ROBERT M
PATEL HITESH K
SPRANKLE KELLY G
CHAO QI
GROTZFELD ROBERT M
PATEL HITESH K
SPRANKLE KELLY G
Application Number:
JP2010194909A
Publication Date:
February 24, 2011
Filing Date:
August 31, 2010
Export Citation:
Assignee:
AMBIT BIOSCIENCES CORP
International Classes:
A61K31/429; A61K31/454; A61K31/496; A61K31/5377; A61K31/541; A61K45/00; A61P1/04; A61P3/10; A61P5/14; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/02; A61P19/02; A61P19/10; A61P25/00; A61P27/16; A61P29/00; A61P31/00; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D513/04
Domestic Patent References:
| JP2001048786A | 2001-02-20 | |||
| JPS5978194A | 1984-05-04 | |||
| JPH06271575A | 1994-09-27 | |||
| JPH11106340A | 1999-04-20 | |||
| JP4610668B2 | 2011-01-12 | |||
| JP2001048786A | 2001-02-20 | |||
| JPS5978194A | 1984-05-04 | |||
| JPH06271575A | 1994-09-27 | |||
| JPH11106340A | 1999-04-20 |
Foreign References:
| GB2056982A | 1981-03-25 | |||
| GB2056982A | 1981-03-25 |
Other References:
JPN5009001869; ＴＯＳＨＩＹＡＳＵ ＭＡＳＥ ＥＴ ＡＬ: 'Ｉｍｉｄａｚｏ［２，１-ｂ］ｂｅｎｚｏｔｈｉａｚｏｌｅｓ． ２． Ｎｅｗ ｉｍｍｕｎｏｓｕｐｐｒｅｓｓｉｖｅ ａｇｅｎｔｓ' ＪＯＵＲＮＡＬ ＯＦ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ Ｖｏｌ．２９， Ｎｏ．３, 1986, ｐ．３８６-３９４, ＡＭＥＲＩＣＡＮ ＣＨＥＭＩＣＡＬ ＳＯＣＩＥＴＹ
JPN5009001872; Ｓ． Ｎ． ＳＡＷＨＮＥＹ ＥＴ ＡＬ: 'ＳＹＮＴＨＥＳＩＳ ＆ ＡＮＴＩＩＮＦＬＡＭＭＡＴＯＲＹ ＡＣＴＩＶＩＴＹ ＯＦ ＳＯＭＥ ＡＲＹＬＩＭＩＤＡＺＯ［２，１-ｂ］ＴＨＩＡＺＯＬＹＬ- ＆ ＡＲＹＬＩＭＩＤＡＺＯ［２，１-ｂ］ＢＥＮＺＯ' ＩＮＤＩＡＮ ＪＯＵＲＮＡＬ ＯＦ ＣＨＥＭＩＳＴＲＹ ＳＥＣＴＩＯＮ Ｂ： ＯＲＧＡＮＩＣ ＡＮＤ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ ｖｏｌ．２１Ｂ， ｎｏ．２, 198202, ｐ．１３４-１３８, ＳＣＩＥＮＴＩＦＩＣ ＰＵＢＬＩＳＨＥＲＳ
JPN5009001869; ＴＯＳＨＩＹＡＳＵ ＭＡＳＥ ＥＴ ＡＬ: 'Ｉｍｉｄａｚｏ［２，１-ｂ］ｂｅｎｚｏｔｈｉａｚｏｌｅｓ． ２． Ｎｅｗ ｉｍｍｕｎｏｓｕｐｐｒｅｓｓｉｖｅ ａｇｅｎｔｓ' ＪＯＵＲＮＡＬ ＯＦ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ Ｖｏｌ．２９， Ｎｏ．３, 1986, ｐ．３８６-３９４, ＡＭＥＲＩＣＡＮ ＣＨＥＭＩＣＡＬ ＳＯＣＩＥＴＹ
JPN5009001872; Ｓ． Ｎ． ＳＡＷＨＮＥＹ ＥＴ ＡＬ: 'ＳＹＮＴＨＥＳＩＳ ＆ ＡＮＴＩＩＮＦＬＡＭＭＡＴＯＲＹ ＡＣＴＩＶＩＴＹ ＯＦ ＳＯＭＥ ＡＲＹＬＩＭＩＤＡＺＯ［２，１-ｂ］ＴＨＩＡＺＯＬＹＬ- ＆ ＡＲＹＬＩＭＩＤＡＺＯ［２，１-ｂ］ＢＥＮＺＯ' ＩＮＤＩＡＮ ＪＯＵＲＮＡＬ ＯＦ ＣＨＥＭＩＳＴＲＹ ＳＥＣＴＩＯＮ Ｂ： ＯＲＧＡＮＩＣ ＡＮＤ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ ｖｏｌ．２１Ｂ， ｎｏ．２, 198202, ｐ．１３４-１３８, ＳＣＩＥＮＴＩＦＩＣ ＰＵＢＬＩＳＨＥＲＳ
JPN5009001872; Ｓ． Ｎ． ＳＡＷＨＮＥＹ ＥＴ ＡＬ: 'ＳＹＮＴＨＥＳＩＳ ＆ ＡＮＴＩＩＮＦＬＡＭＭＡＴＯＲＹ ＡＣＴＩＶＩＴＹ ＯＦ ＳＯＭＥ ＡＲＹＬＩＭＩＤＡＺＯ［２，１-ｂ］ＴＨＩＡＺＯＬＹＬ- ＆ ＡＲＹＬＩＭＩＤＡＺＯ［２，１-ｂ］ＢＥＮＺＯ' ＩＮＤＩＡＮ ＪＯＵＲＮＡＬ ＯＦ ＣＨＥＭＩＳＴＲＹ ＳＥＣＴＩＯＮ Ｂ： ＯＲＧＡＮＩＣ ＡＮＤ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ ｖｏｌ．２１Ｂ， ｎｏ．２, 198202, ｐ．１３４-１３８, ＳＣＩＥＮＴＩＦＩＣ ＰＵＢＬＩＳＨＥＲＳ
JPN5009001869; ＴＯＳＨＩＹＡＳＵ ＭＡＳＥ ＥＴ ＡＬ: 'Ｉｍｉｄａｚｏ［２，１-ｂ］ｂｅｎｚｏｔｈｉａｚｏｌｅｓ． ２． Ｎｅｗ ｉｍｍｕｎｏｓｕｐｐｒｅｓｓｉｖｅ ａｇｅｎｔｓ' ＪＯＵＲＮＡＬ ＯＦ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ Ｖｏｌ．２９， Ｎｏ．３, 1986, ｐ．３８６-３９４, ＡＭＥＲＩＣＡＮ ＣＨＥＭＩＣＡＬ ＳＯＣＩＥＴＹ
JPN5009001872; Ｓ． Ｎ． ＳＡＷＨＮＥＹ ＥＴ ＡＬ: 'ＳＹＮＴＨＥＳＩＳ ＆ ＡＮＴＩＩＮＦＬＡＭＭＡＴＯＲＹ ＡＣＴＩＶＩＴＹ ＯＦ ＳＯＭＥ ＡＲＹＬＩＭＩＤＡＺＯ［２，１-ｂ］ＴＨＩＡＺＯＬＹＬ- ＆ ＡＲＹＬＩＭＩＤＡＺＯ［２，１-ｂ］ＢＥＮＺＯ' ＩＮＤＩＡＮ ＪＯＵＲＮＡＬ ＯＦ ＣＨＥＭＩＳＴＲＹ ＳＥＣＴＩＯＮ Ｂ： ＯＲＧＡＮＩＣ ＡＮＤ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ ｖｏｌ．２１Ｂ， ｎｏ．２, 198202, ｐ．１３４-１３８, ＳＣＩＥＮＴＩＦＩＣ ＰＵＢＬＩＳＨＥＲＳ
Attorney, Agent or Firm:
Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki