Title:
Akt活性の阻害剤
Document Type and Number:
Japanese Patent JP2007532551
Kind Code:
A
Abstract:
The present invention is directed to compounds which contain substituted napthyridines which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
Inventors:
Bilodo, Mark Tay
Chien, chi chi
Kosuf Aude, Nicholas Day Pee
Eastman, Brian Davrill
Heartnet, Jiyoung Shee
Fu, Etsusa H
Manley, peter theay
Neilson, Lou Ann
Terrani, Lida Earl
Woo Ji Kai
Chien, chi chi
Kosuf Aude, Nicholas Day Pee
Eastman, Brian Davrill
Heartnet, Jiyoung Shee
Fu, Etsusa H
Manley, peter theay
Neilson, Lou Ann
Terrani, Lida Earl
Woo Ji Kai
Application Number:
JP2007507448A
Publication Date:
November 15, 2007
Filing Date:
April 05, 2005
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07D471/04; A61K31/4375; A61K31/444; A61K31/4709; A61K31/497; A61K31/4995; A61K31/506; A61K31/519; A61K31/5377; A61P17/02; A61P17/06; A61P35/00; A61P35/02; A61P43/00; C07D487/04; C12N9/99; C12N15/09
Domestic Patent References:
| JP4616831B2 | 2011-01-19 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura