質量分析によるインスリンの定量

Japanese Patent JP7399200

B2

Methods are described for determining the amount of insulin in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying insulin in a biological sample utilizing purification methods coupled with tandem mass spectrometric or high resolution/high accuracy mass spectrometric techniques.

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Chen, Shaoui
Clark, Nigel

JP2022011514A

December 15, 2023

January 28, 2022

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Quest Diagnostics Investments Incorporated

G01N27/62; G01N1/40; G01N30/72; G01N30/88; G01N33/68

US20060219558

THEVIS et al.,Current role of LC-MS(/MS) in doping control,ANALYTICAL AND BIOANALYTICAL CHEMISTRY,ドイツ,2007年01月30日,vol. 388, no. 7,1351-1358
FIERENS et al.,Strategies for determination of insulin with tandem electrospray mass spectrometry:implications for,Rapid Communications in Mass Spectrometry,2001年,15,1433-1441
THEVIS,M et al.,Mass spectrometric determination of insulins and their degradation products in sports drug testing,MASS SPECTROMETRY REVIEWS,2008年,27,35-50
TIIA KUURANNE et al.,Insulins in equine urine: qualitative analysis by immunoaffinity purification and liquid chromatography/tandem mass spectrometry for doping control purposes in horse-racing,RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2008年02月15日,vol. 22, no. 3,355-362

Hiroshi Kobayashi
Norio Omori

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