LIPOXIN ANALOG AS NEW ANGIOGENESIS INHIBITOR

Title:

LIPOXIN ANALOG AS NEW ANGIOGENESIS INHIBITOR

Document Type and Number:

Japanese Patent JP2010059183

Kind Code:

A

Abstract:

To provide a method for preventing or restraining angiogenesis.

This pharmaceutical composition for preventing, alleviating or restraining angiogenesis comprises 15-epi-16-(para-fluoro)-phenoxy-lipoxin A4, LXA4, 15-epi-LXA4 or 15-R/S-methyl, LXA4 and their pharmaceutically acceptable salts, esters, amides, carboxylic acids, or prodrugs.

Inventors:

SERHAN CHARLES N
FIERRO IOLANDA M

Application Number:

JP2009256184A

Publication Date:

March 18, 2010

Filing Date:

November 09, 2009

Export Citation:

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Assignee:

BRIGHAM & WOMENS HOSPITAL

International Classes:

A61K31/20; A61K31/16; A61K31/202; A61K31/23; A61K31/232; A61P9/00; A61P9/08; A61P9/10; A61P17/02; A61P27/02; A61P35/00; A61P43/00

Foreign References:

WO1998011049A1	1998-03-19
WO1994029262A1	1994-12-22
WO2000054767A1	2000-09-21
WO2000055109A1	2000-09-21
WO1998011049A1	1998-03-19
WO1994029262A1	1994-12-22
WO2000054767A1	2000-09-21
WO2000055109A1	2000-09-21

Other References:

JPN5005008365; ＣＬＡＲＩＡ　Ｊ: ＭＯＬＥＣＵＬＡＲ　ＭＥＤＩＣＩＮＥＶ２　Ｎ５, 199609, Ｐ５８３-５９６
JPN5005008366; ＦＩＥＲＲＯ　ＩＯＬＡＮＤＡ　Ｍ: ＦＡＳＥＢ　ＪＯＵＲＮＡＬＶ１５　Ｎ５, 20010308
JPN5005008367; ＣＬＩＳＨ　ＣＬＡＲＹ　Ｂ: ＰＲＯＣＥＥＤＩＮＧＳ　ＯＦ　ＴＨＥ　ＮＡＴＩＯＮＡＬ　ＡＣＡＤＥＭＹ　ＯＦ　ＳＣＩＥＮＣＥＳ　ＯＦ　ＴＨＥ　ＵＮＩＴＥＤ　ＳＴＡＴＥＳＶ９６　Ｎ１４, 19990706, Ｐ８２４７-８２５２
JPN5005008365; ＣＬＡＲＩＡ　Ｊ: ＭＯＬＥＣＵＬＡＲ　ＭＥＤＩＣＩＮＥＶ２　Ｎ５, 199609, Ｐ５８３-５９６
JPN5005008366; ＦＩＥＲＲＯ　ＩＯＬＡＮＤＡ　Ｍ: ＦＡＳＥＢ　ＪＯＵＲＮＡＬＶ１５　Ｎ５, 20010308
JPN5005008367; ＣＬＩＳＨ　ＣＬＡＲＹ　Ｂ: ＰＲＯＣＥＥＤＩＮＧＳ　ＯＦ　ＴＨＥ　ＮＡＴＩＯＮＡＬ　ＡＣＡＤＥＭＹ　ＯＦ　ＳＣＩＥＮＣＥＳ　ＯＦ　ＴＨＥ　ＵＮＩＴＥＤ　ＳＴＡＴＥＳＶ９６　Ｎ１４, 19990706, Ｐ８２４７-８２５２

Attorney, Agent or Firm:

Patent business corporation Odashima patent office

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