Title:
ENGINEERED TRANSAMINASE POLYPEPTIDES FOR INDUSTRIAL BIOCATALYSIS
Document Type and Number:
Japanese Patent JP2022062113
Kind Code:
A
Abstract:
To provide engineered transaminases that can be used in industrial processes for preparing chiral amine compounds in an optically active form.SOLUTION: The present invention provides methods of making engineered polypeptides having transaminase activity, polynucleotides encoding the polypeptides; methods of making the polypeptides; and methods of using the polypeptides for the biocatalytic conversion of amino acceptor substrate compounds (i.e., keto group containing compounds) to chiral amine product compounds.SELECTED DRAWING: None
Inventors:
SCOTT J NOVICK
NIKKI DELLAS
OSCAR ALVIZO
RAVI DAVID GARCIA
CHARLENE CHING
DAVID ENTWISTLE
NIKKI DELLAS
OSCAR ALVIZO
RAVI DAVID GARCIA
CHARLENE CHING
DAVID ENTWISTLE
Application Number:
JP2022010034A
Publication Date:
April 19, 2022
Filing Date:
January 26, 2022
Export Citation:
Assignee:
CODEXIS INC
International Classes:
C12N15/54; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/10; C12N15/63; C12P21/02
Domestic Patent References:
| JP2016501544A | 2016-01-21 | |||
| JP2016516744A | 2016-06-09 |
Foreign References:
| WO2010081053A2 | 2010-07-15 |
Other References:
ACS CATALYSIS, vol. 6, JPN6021004106, 4 October 2016 (2016-10-04), pages 7749 - 7759, ISSN: 0004948483
Attorney, Agent or Firm:
Shusaku Yamamoto
Morishita Natsuki
Morishita Natsuki