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Title:
METHOD FOR DECIDING EFFICACY OF INFLIXIMAB MEDICINAL EFFECT IN PATIENT WITH RHEUMATOID ARTHRITIS
Document Type and Number:
Japanese Patent JP2011004743
Kind Code:
A
Abstract:

To provide a method for efficiently and effectively discriminating the presence or absence of the efficacy of an infliximab administering on a gene level by analyzing the gene expression profile of a blood sample.

The method for discriminating the efficacy of the infliximab medicinal effect in a patient with rheumatoid arthritis using one or more indicators selected from a plurality of indicators includes: a process for measuring the expression level of one or more genes selected from a specific group in blood of the patient with rheumatoid arthritis; a process for analyzing the measured expression level, using the gene expression profile prepared beforehand; and a process for discriminating the efficacy of infliximab medicinal effect in the patient with rheumatoid arthritis based on the analysis result.


Inventors:
YANO MOTOHIKO
MATOBA AKIRA
NAKAMURA SEIJI
SHIMODA MASABUMI
MATSUBARA KENICHI
TAKEUCHI TSUTOMU
OKAYAMA TOSHIJI
TAMURA TAKURO
Application Number:
JP2010145428A
Publication Date:
January 13, 2011
Filing Date:
June 25, 2010
Export Citation:
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Assignee:
DNA CHIP RESEARCH INC
International Classes:
C12Q1/68; C12M1/00; C12N15/09; G01N33/53; G01N37/00
Other References:
JPN6014047256; 医療と検査機器・試薬 Vol.28, No.2, 2005, pp.177-190
JPN6014047257; 肺癌 Vol.46, No.3, 2006, pp.245-251
Attorney, Agent or Firm:
Taro Yaguchi
Yoshiyuki Sasaki
Kazuya Sekiguchi