Title:
METHOD FOR PRODUCING AZETIDINONE COMPOUND
Document Type and Number:
Japanese Patent JP2003277390
Kind Code:
A
Abstract:
To provide a method for selectively producing a desired synthetic intermediate for a carbapenem antibacterial agent having a methyl group at the 1'-β site under a mild condition in short steps in high yield and free from the problems inherent to conventional methods.
The azetidinone compound having a 1'-β configuration is produced by carrying out the reaction of the formula (R1 is H or an OH-protecting group; L is an eliminable group; R2 is H or a lower alkyl; R3 is an alkyl, an aralkyl or the like; and X is O or S) in the presence of a specific metal compound and a base.
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Inventors:
MATSUMOTO TAKASHI
MURAYAMA TOSHIYUKI
MOROI TAKASHI
MURAYAMA TOSHIYUKI
MOROI TAKASHI
Application Number:
JP2002082560A
Publication Date:
October 02, 2003
Filing Date:
March 25, 2002
Export Citation:
Assignee:
TAKASAGO PERFUMERY CO LTD
International Classes:
C07B61/00; C07D205/08; C07F7/18; (IPC1-7): C07F7/18
Attorney, Agent or Firm:
Norio Saeki