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Title:
METHOD FOR PRODUCING MEDICINE-INCLUDING LIPOSOME AND APPARATUS FOR PRODUCING MEDICINE-INCLUDNING LIPOSOME
Document Type and Number:
Japanese Patent JP2011140468
Kind Code:
A
Abstract:

To produce a liposome having a high inclusion ratio of medicine without using an organic solvent and enlarging an apparatus.

A solution containing a liposome and a medicine is circulated through a microcapillary 13 so as to form a laminar flow. A part of the microcapillary 13 is regulated in temperature and arranged in a temperature-regulating ultrasonic tank 12 for irradiating the solution with ultrasonic waves. The solution that forms a laminar flow and contains the liposome and the medicine is irradiated with ultrasonic waves. The liposome having a high inclusion ratio of medicine is contained in the solution after ultrasonic irradiation.


Inventors:
YAMASHITA KENICHI
MAEDA HIDEAKI
MIYAZAKI MASAYA
NAKAMURA HIROYUKI
UEHARA MASAHITO
Application Number:
JP2010002584A
Publication Date:
July 21, 2011
Filing Date:
January 08, 2010
Export Citation:
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Assignee:
NAT INST OF ADVANCED IND SCIEN
International Classes:
A61K9/127
Attorney, Agent or Firm:
Nobuo Nishiki
Tomohiro Matsuda