METHOD FOR PRODUCING OXIDATION TYPE POLYPEPTIDE WHICH CONTAIN OXIDIZED SULFUR-CONTAINING AMINO ACID RESIDUE

Title:

METHOD FOR PRODUCING OXIDATION TYPE POLYPEPTIDE WHICH CONTAIN OXIDIZED SULFUR-CONTAINING AMINO ACID RESIDUE

Document Type and Number:

Japanese Patent JP2007319084

Kind Code:

A

Abstract:

To provide a method for producing an oxidation type polypeptide which contains oxidized sulfur-containing amino acid residues.

This method for producing the oxidation type polypeptide, comprising oxidizing a polypeptide containing a sulfur-containing amino acid selected from the group consisting of cysteine and methionine to produce the oxidation type polypeptide containing at least one oxidation type sulfur-containing amino acid selected from the group consisting of cysteine sulfonic acid or its salts, and methionine sulfoxide, is characterized by treating the culture product of a transformed host transformed with a gene encoding the polypeptide with an oxidizing agent and then recovering the produced oxidation type polypeptide.

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Inventors:

SAITO YOSHIRO
KINUMI TOMOYA
NISHIO KEIKO
OGAWA YOKO
YOSHIDA KOICHI
FUTAKI TOKIO

Application Number:

JP2006153039A

Publication Date:

December 13, 2007

Filing Date:

June 01, 2006

Export Citation:

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Assignee:

NAT INST OF ADV IND & TECHNOL

International Classes:

C12P21/02; C12N15/09

Foreign References:

WO2005075513A1

2005-08-18

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