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Title:
METHOD FOR USING AND DETECTING RELATED ANTIGEN IN URINE AND ANTIGEN SUB UNIT
Document Type and Number:
Japanese Patent JP3429281
Kind Code:
B2
Abstract:

PROBLEM TO BE SOLVED: To provide a antigenicity polypeptide sub-unit of a tumor-associated antigen in urine that has a molecular weight of approximately 90-100 kD after reduction by β-mercaptoethanol and separation by SDS-polyacrylamide gel cataphoresis and is essentially refined, and to provide a method for detecting a monoclonal antibody and a tumor, an immunotreatment method, a method for monitoring malignancy, a method for detecting tumor-associated antigen in urine, and a vaccine related to the tumor-associated antigen in urine and other methods.
SOLUTION: The method for detecting anti-U-TAA antibody in a sample includes a process for providing a surface where U-TAA is combined (i), a process for bringing the sample into contact with the surface (ii), and a process for detecting the anti-U-TAA antibody on the surface.


Inventors:
Donald El. Morton
Rishab Kay. Gupta
David M. Youhus
Application Number:
JP2001060998A
Publication Date:
July 22, 2003
Filing Date:
October 31, 1990
Export Citation:
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Assignee:
Donald El. Morton
Rishab Kay. Gupta
David M. Youhus
International Classes:
A61K39/00; A61K39/395; A61K47/48; A61K49/00; A61P35/00; C07K14/435; C07K14/47; C07K16/00; C07K16/30; C07K16/42; C12N15/02; C12N15/09; C12P21/08; C12Q1/68; G01N33/53; G01N33/531; G01N33/535; G01N33/564; G01N33/574; G01N33/577; A61K38/00; C12R1/91; (IPC1-7): G01N33/574; G01N33/53; G01N33/564
Other References:
Cancer Immunology Immotherapy Vol.29,No.4(1989)p.247−254
Attorney, Agent or Firm:
Shusaku Yamamoto