Title:
METHODS FOR ASSESSING ENDOMETRIUM RECEPTIVITY OF PATIENT
Document Type and Number:
Japanese Patent JP2016171802
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a method for assessing the human endometrium receptivity that will help increasing pregnancy rates after a controlled ovarian hyperstimulation (COH) and in vitro fertilization (IVF); and to provide a biomarker thereof.SOLUTION: A method for assessing the endometrium receptivity of a patient comprises i) a step consisting of measuring the expression level of eleven genes in an endometrial biopsy sample obtained from the patient wherein the genes are MFAP5, ANGPTL1, PROK1, NLF2, LAMB3, BCL2L10, CD68, TRPC4, SORCS1, FST and KRT80; ii) a step of comparing the expression level of the genes in the endometrial biopsy sample with a control, wherein detecting differential in the expression level of the genes between the endometrial biopsy sample and the control is indicative whether the endometrium is receptive.SELECTED DRAWING: None
Inventors:
SAMIR HAMAMAH
DELPHINE HAOUZI
DELPHINE HAOUZI
Application Number:
JP2016086087A
Publication Date:
September 29, 2016
Filing Date:
April 22, 2016
Export Citation:
Assignee:
INST NATL DE LA SANTE & DE LA RECH MEDICAL
CENTRE HOSPITALIER UNIV AIRE DE MONTPELLIER
UNIV MONTPELLIER
CENTRE HOSPITALIER UNIV AIRE DE MONTPELLIER
UNIV MONTPELLIER
International Classes:
C12Q1/68; C12N5/071; C12N5/073; G01N33/50
Domestic Patent References:
| JP000629164B |
Attorney, Agent or Firm:
Patent business corporation Tsukuni