Title:
ソリシジン由来ペプチドならびにＴＲＰＶ−６がんの検出および薬剤送達のための方法
Document Type and Number:
Japanese Patent JP5836940
Kind Code:
B2
Abstract:
Compounds containing TRPV6-binding peptides and their use in the detection and diagnosis of cancer are described. Also described are methods for detecting and staging cancer that use the compounds of the invention. Compounds containing TRPV6-binding peptides are useful for the delivery of diagnostic and therapeutic agents to cells or tumors that express TRPV6.
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Inventors:
John M Stewart
Application Number:
JP2012516450A
Publication Date:
December 24, 2015
Filing Date:
June 28, 2010
Export Citation:
Assignee:
Solicimed BioPharma Incorporated
International Classes:
C07K14/47; A61K38/00; A61K45/00; A61K49/00; A61P35/00; A61P43/00; C12Q1/68; G01N33/53; G01N33/536; A61K33/242
Foreign References:
| WO2009114943A1 | ||||
| US20070020251 |
Other References:
PREVARSKAYA, N. et al.,"TRP channels in cancer.",BIOCHIM. BIOPHYS. ACTA,2007年 8月,Vol.1772, No.8,P.937-946
BODDING, M.,"TRP proteins and cancer.",CELL. SINGAL.,2007年 3月,Vol.19, No.3,P.617-624
DEN DEKKER, E. et al.,"The epithelial calcium channels, TRPV5 & TRPV6: from identification towards regulation.",CELL CALCIUM,2003年 5月,Vol.33, No.5-6,P.497-507
BOWEN, C.V. et al.,"In vivo detection of human TRPV6-rich tumors with anti-cancer peptides derived from soricidin.",PLOS ONE,2013年 3月15日,Vol.8, No.3,e58866(P.1-11)
BODDING, M.,"TRP proteins and cancer.",CELL. SINGAL.,2007年 3月,Vol.19, No.3,P.617-624
DEN DEKKER, E. et al.,"The epithelial calcium channels, TRPV5 & TRPV6: from identification towards regulation.",CELL CALCIUM,2003年 5月,Vol.33, No.5-6,P.497-507
BOWEN, C.V. et al.,"In vivo detection of human TRPV6-rich tumors with anti-cancer peptides derived from soricidin.",PLOS ONE,2013年 3月15日,Vol.8, No.3,e58866(P.1-11)
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
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