Title:
NEW PRODUCTION OF PHOSPHONATE DIESTER
Document Type and Number:
Japanese Patent JP3863956
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a new method for producing the subject compound by reacting an epoxide with the magnesium halide salt of a phosphite diester, enabling to obtain the compound from the epoxide in a good yield.
SOLUTION: This method for producing a phosphonate diester of formula III or IV comprises reacting an epoxide of formula I(R1-R4 are each a substituent) with a phosphite diester magnesium halide salt of formula II (R5, R6 are each a hydrocarbon group which may be substituted; X is a halogen). Therein, the compound of formula II is addition-reacted to the compound of formula I, and the magnesium halide in the addition reaction product is substituted by a proton. The reaction is preferably carried out in an etheric solvent such as dioxane at a temperature of -60 to -40°C. The compound of formula II is preferably obtained by reacting a phosphite diester such as di(phenylmethyl) phosphite ester with a Grignard reagent of the formula: R7MgX (R7 is a hydrocarbon group which may be substituted) such as methyl magnesium bromide.
Inventors:
Kazuhiko Nakamura
Application Number:
JP35924696A
Publication Date:
December 27, 2006
Filing Date:
December 30, 1996
Export Citation:
Assignee:
Kazuhiko Nakamura
Kureha Co., Ltd.
Kureha Co., Ltd.
International Classes:
C07F9/40; C07F9/09; (IPC1-7): C07F9/40
Domestic Patent References:
| JP50028420A | ||||
| JP42026621B1 | ||||
| JP36007871B1 | ||||
| JP10182676A |
Attorney, Agent or Firm:
Kiyoshi Fujino
Kiyonori Fujino
Kyoko Yoshimi
Kiyonori Fujino
Kyoko Yoshimi
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