Title:
NEW REAGENT FOR SYNTHESIZING TETRAZOLE COMPOUND AND PRODUCTION OF TETRAZOLE COMPOUND USING THE SAME
Document Type and Number:
Japanese Patent JPH08325248
Kind Code:
A
Abstract:
PURPOSE: To obtain at low cost the subject safe and highly versatile reagent with many kinds of usable solvents, useful for producing 1H-tetrazoles from carbonitriles, composed of an alkali metal azide and zinc chloride.
CONSTITUTION: This new reagent is composed of (A) an alkali metal azide (pref. sodium azide) and (B) zinc chloride. Using this reagent, a 1H-tetrazole compound of the formula is produced from a carbonitrile compound of the formula R-CN (R is a substituent). In this case, the reaction is carried out normally under normal pressures at 50-150°C for 30min to 24h. When benzonitrile is used as the carbonitrile compound, 5-phenyl-1H-tetrazole is obtained as the compound of the formula.
Inventors:
TOKUHARA GINROU
YAMAGUCHI TADASHI
IWASAKI TETSUYA
YAMAGUCHI TADASHI
IWASAKI TETSUYA
Application Number:
JP12857695A
Publication Date:
December 10, 1996
Filing Date:
May 26, 1995
Export Citation:
Assignee:
CHUGOKU KAYAKU
WAKUNAGA PHARMA CO LTD
WAKUNAGA PHARMA CO LTD
International Classes:
C01G9/04; C07D257/04; C07D401/12; C07D403/10; C07D403/12; C07D413/10; C07D417/10; C07D471/04; C07D401/10; (IPC1-7): C07D257/04; C01G9/04; C07D401/10; C07D401/12; C07D403/10; C07D403/12; C07D413/10; C07D417/10; C07D471/04
Attorney, Agent or Firm:
Kyozo Yuasa (6 people outside)
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