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Title:
新規HPV16非HLA拘束性T細胞ワクチン、その組成物及び使用方法
Document Type and Number:
Japanese Patent JP7397945
Kind Code:
B2
Abstract:
Novel human papillomovirus immunogenic compositions and methods of use thereof are provided. The compositions comprise unique combinations of multi-epitope peptide sequences specifically selected and designed to be effectively processed and cross-presented to T-cells. The peptides utilized in the compositions display high levels of binding with HLA-supertypes. The immunogenic compositions are broadly applicable to large proportions of target populations. The compositions comprise adjuvants such as cationic lipids.

Inventors:
Frank Bedu-Add
Greg Conn
Martin Ward
Jerold Woodward
Application Number:
JP2022169842A
Publication Date:
December 13, 2023
Filing Date:
October 24, 2022
Export Citation:
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Assignee:
PDS BIOTECHNOLOGY CORPORATION
International Classes:
A61K39/12; A61K9/127; A61K39/39; A61K47/18; A61K47/24; A61K47/54; A61K47/60; A61P31/20; A61P37/04
Domestic Patent References:
JP2010537961A
JP2003509035A
JP2012526853A
Foreign References:
WO2013188627A2
WO2015061416A2
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Ryotaro Takei



 
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