NOVEL ISOCYANATE - BAKER INSTR CORP

Title:

NOVEL ISOCYANATE

Document Type and Number:

Japanese Patent JPS5823699

Kind Code:

A

Abstract:

Isocyanates of formula (I) are new (R)3.SiO.R1.NCO (I) (where R is alkyl, alicyclic, aryl, alkaryl or aralkyl, all being 11C; R1 is (i) -CH2:CH2-, (ii) A pref. reagent, 2-(4-trimethylsiloxyphenyl)ethyl isocyanate was prepd. by addition of trimethylchlorosilane to a mixture of tyramine and NEt3 in tetrahydrofuran, then bubbling CO2 through the mixt. (I) are reagents which permit labelling of cpds. for subsequent assay. e.g. in body fluids.

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Inventors:

UIRIAMU ANTONII AIZENHARUTO JI
EDEII HEDAYA
SUPIROSU TEODOROPIYUROSU

Application Number:

JP11182882A

Publication Date:

February 12, 1983

Filing Date:

June 30, 1982

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Assignee:

BAKER INSTR CORP

International Classes:

A61K31/695; C07D401/04; C07F7/10; C07D307/58; C07F7/18; C07J41/00; G01N33/53; G01N33/534; (IPC1-7): A61K31/695; C07F7/18; G01N33/56

Other References:

CHEMICAL ABSTRACTS=1973
CHEMICAL ABSTRACTS=1969

Attorney, Agent or Firm:

Motohiro Kurauchi

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