To provide a highly stereoselective polymer-carried allylsilane compound which is suitable for the solid phase reaction with various compounds to produce an optically active compound, and its production method and use.
This allylsilane compound is represented by formula (1) (wherein the group at the left side of L is a polymer carrier; L is a linker; RA and RB are each an alkyl or phenyl group; and R1, R3 and R4 are each H or an optionally substituted alkyl, cycloalkyl, aryl, or aromatic heterocyclic group) and is prepared by causing a polymer carrier to carry an allylsilyl. This compound can produce various compounds by the solid phase reaction with aldehydes, ketones, etc., is suitable especially for producing an optically active compound, and is useful as a reaction material for medicines, etc.
SUGINOME MICHINORI