PROTEIN ESTIMATED TO BIND TO ATP AND NUCLEIC ACID AND HAVE PROPERTIES OF HELICASE AND ATPASE

Title:

PROTEIN ESTIMATED TO BIND TO ATP AND NUCLEIC ACID AND HAVE PROPERTIES OF HELICASE AND ATPASE

Document Type and Number:

Japanese Patent JPH09173087

Kind Code:

A

Abstract:

To obtain a DNA useful for producing RNA helicase having anticarclnogenic, antiatherosclerosis, immunodepressive, antiinflammatory, antiviral, antifungal and antibacterial activities, etc.

This DNA codes a protein or its part which can bind to nucleic acid, has properties of a helicase and ATPase on estimation and whose mRNA increases the expression under the influence of leflunomide, and especially has a DNA sequence of the formula. The DNA is originated from the derivatives of a human cell strain or mouse cell strain A20.2J, and can be obtained e.g. by screening a cDNA bank prepared from a human skeletal muscle with a sequence of hs1/hs2.

Inventors:

BERUNTO KIRUSHIYUBAUMU
SHIYUTEFUAN MIYURUNAA
ROBAATO BAATORETSUTO

Application Number:

JP33628096A

Publication Date:

July 08, 1997

Filing Date:

December 03, 1996

Export Citation:

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Assignee:

HOECHST AG

International Classes:

C12N15/09; C07K14/00; C07K14/47; C12N5/10; C12N9/90; C12N15/55; C12Q1/68; C12Q1/6823; C12Q1/6886; A61K38/00; (IPC1-7): C12N15/09; C07K14/00; C12N5/10; C12Q1/68

Attorney, Agent or Firm:

Chika Takagi (2 outside)

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