Title:
SPHINGOLIPID-SURFACTANT COMPLEX
Document Type and Number:
Japanese Patent JP3817354
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To obtain the subject complex excellent in water dispersibility and capable of readily emulsifying and solubilizing by removing an organic solvent from an organic solvent solution in which sphingolipid, etc., and a surfactant are uniformly dissolved in the organic solvent to simultaneously deposit the sphingolipid and the surfactant.
SOLUTION: This complex is obtained by removing an organic solvent from an organic solvent solution obtained by uniformly dissolving a sphingolipid (e.g. ceramide or cerebroside) or a substance having a structure analogous to the lipid and a surfactant into the organic solvent. The surfactant is preferably lecithin (e.g. soybean lecithin or yolk lecithin), a saccharide fatty acid ester (e.g. saccharide monoplamitate), a di-long chain alkyl quaternary ammonium salt type cation (e.g. distearyldimethyl ammonium chloride). The compounding ratio of the sphingolipid to the surfactant in the complex is preferably (1-70):(30-99) wt.%.
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Inventors:
Mikinobu Sato
Nobuaki Hattori
Masakazu Okumura
Nobuaki Hattori
Masakazu Okumura
Application Number:
JP371098A
Publication Date:
September 06, 2006
Filing Date:
January 12, 1998
Export Citation:
Assignee:
Nippon Seika Co., Ltd.
International Classes:
A61K8/63; A61K8/68; A61K8/00; A61K8/40; A61K8/55; A61K8/58; A61K8/73; A61K31/16; A61K31/164; A61K31/575; A61P17/00; A61P17/16; A61Q19/00; (IPC1-7): A61K7/48; A61K7/00; A61K7/00; A61K31/16; A61K31/575
Domestic Patent References:
| JP1299265A | ||||
| JP64025716A | ||||
| JP9508900A | ||||
| JP9315929A | ||||
| JP63275506A | ||||
| JP11130651A | ||||
| JP9301820A | ||||
| JP7033637A | ||||
| JP2048520A | ||||
| JP4193814A |
Foreign References:
| WO1998000092A1 |