Title:
タンパク質キナーゼ阻害剤としてのスクアリン酸誘導体
Document Type and Number:
Japanese Patent JP2009502820
Kind Code:
A
Abstract:
Compounds of the formula I, in which R, X, R1, R2, R3, R4 and R5 have the meanings indicated in Claim 1, are inhibitors of CHK1 CHK2 and SGK kinases and can be employed, inter alia, for the treatment of cancer.
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Inventors:
Mederski, Varner
Ende, Ulrich
Berniel, Gerhard
Zenke, frank
Greiner, Hartmut
Steaver, frank
Ende, Ulrich
Berniel, Gerhard
Zenke, frank
Greiner, Hartmut
Steaver, frank
Application Number:
JP2008523156A
Publication Date:
January 29, 2009
Filing Date:
June 30, 2006
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07C225/20; A61K31/137; A61K31/40; A61K31/415; A61K31/4164; A61K31/4402; A61K31/47; A61K31/472; A61K31/4965; A61K31/50; A61K31/505; A61K45/00; A61P1/04; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P9/04; A61P9/10; A61P9/12; A61P11/00; A61P11/08; A61P13/12; A61P17/00; A61P19/02; A61P25/28; A61P27/06; A61P27/12; A61P27/16; A61P29/00; A61P31/04; A61P35/00; A61P35/04; A61P43/00; C07C221/00; C07D207/335; C07D213/36; C07D213/61; C07D213/84; C07D215/12; C07D217/04; C07D231/12; C07D233/64; C07D237/08; C07D239/26; C07D241/12; C07F5/02; C07B53/00
Attorney, Agent or Firm:
Akio Miyazaki
Ishibashi Masayuki
Masaaki Ogata
Ishibashi Masayuki
Masaaki Ogata