Title:
細胞周期-キナーゼまたはレセプター-チロシン-キナーゼインヒビターとしての置換2-置換アニリノピリミジン類、それらの製造および薬剤としての使用
Document Type and Number:
Japanese Patent JP2008514571
Kind Code:
A
Abstract:
This invention relates to pyrimidine derivatives of general formula I in which R1, R2, R3, R4, A and D have the meanings that are contained in the description, as inhibitors of cyclin-dependent kinases and VEGF receptor tyrosine kinases, their production as well as their use as medications for treating various diseases.
Inventors:
Clefé, Arbeto
Backpacking, Ulrich
West, Christopher
Bream, hans
G-Meister, Gerhard
Kruger, Martin
Yauterat, Rolf
Linau, Philip
Backpacking, Ulrich
West, Christopher
Bream, hans
G-Meister, Gerhard
Kruger, Martin
Yauterat, Rolf
Linau, Philip
Application Number:
JP2007532863A
Publication Date:
May 08, 2008
Filing Date:
September 27, 2005
Export Citation:
Assignee:
Bayer Schering Pharma Aktiengesellschaft
International Classes:
C07D239/47; A61K31/505; A61P1/00; A61P1/16; A61P9/00; A61P9/10; A61P13/12; A61P15/08; A61P17/06; A61P17/14; A61P17/16; A61P19/02; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P31/00; A61P31/12; A61P31/18; A61P35/00; A61P35/02; A61P37/00; A61P37/02; C07D239/48
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura