Title:
ダポキセチンを含む時間差徐放性経口投与型の薬学的組成物
Document Type and Number:
Japanese Patent JP2013530220
Kind Code:
A
Abstract:
The present invention relates to a time-delayed sustained release pharmaceutical composition for oral administration, which comprises an immediate release phase and a prolonged sustained release phase, wherein said immediate release phase and prolonged sustained release phase respectively comprise Dapoxetine therein as an active ingredient. The pharmaceutical composition of the present invention comprises Dapoxetine, which is an agent for treating premature ejaculation, in both the immediate release phase and the prolonged sustained release phase thereof, to thereby immediately exhibit the effectiveness of the pharmaceutical composition of the present invention in order to enable a patient to achieve sexual satisfaction during the early stage of administration, as well as to reduce side effects by means of the time-delayed sustained release of the prolonged sustained release phase during the early stage of administration and enable a continuous in vivo absorption of Dapoxetines, to thereby lengthen the duration of the effectiveness of the pharmaceutical composition of the present invention. Further, agents for treating erectile dysfunction, such as sildenafil, tadalifil or the like can be added to the immediate release phase so as to allow for a coincidence of the durations of the effectiveness of a premature ejaculation treatment agent and erectile dysfunction treatment agents, even though a half-life difference exists between the two types of treatment agents, thus maximizing patient satisfaction.
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Inventors:
Lee, Chang-Kyo
Park, Sun-Geun
Park, Sun-Geun
Application Number:
JP2013518273A
Publication Date:
July 25, 2013
Filing Date:
July 05, 2011
Export Citation:
Assignee:
Navi Farm. Company Limited
International Classes:
A61K31/137; A61K9/16; A61K9/20; A61K9/24; A61K9/48; A61K9/52; A61K31/519; A61K45/00; A61P15/00; A61P43/00
Attorney, Agent or Firm:
Longhua International Patent Service Corporation