Title:
【発明の名称】抗ピコルナウィルス化合物及び組成物、その医薬的使用、並びにその合成のための物質
Document Type and Number:
Japanese Patent JP2003506457
Kind Code:
A
Abstract:
Compounds of the formula:where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.
Inventors:
Dragovich, Peter Scott
Butterfly, roux
Webber, Stephen Evan
Prince, Thomas Jay
Leach, Siegfried Heinz
Kefart, Susan Yee
Louis, Yuan Jin
Butterfly, roux
Webber, Stephen Evan
Prince, Thomas Jay
Leach, Siegfried Heinz
Kefart, Susan Yee
Louis, Yuan Jin
Application Number:
JP2001515702A
Publication Date:
February 18, 2003
Filing Date:
August 03, 2000
Export Citation:
Assignee:
Agron Pharmaceuticals Incorporated
International Classes:
A61K31/381; A61K31/4015; A61K31/426; A61K31/428; A61K31/44; A61K31/445; A61K38/06; A61P31/12; A61P31/14; A61P31/16; A61P43/00; C07D207/26; C12N9/99; C07D417/06; C07K5/00; C07K5/02; C07K5/06; C07K5/08; C07K5/083; C07K5/097; A61K38/00; (IPC1-7): C07K5/08; A61K31/381; A61K31/4015; A61K31/426; A61K31/428; A61K31/44; A61K31/445; A61P31/12; A61P31/16; A61P43/00; C07K5/083; C12N9/99
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)