Title:
【発明の名称】薬学的作用物質の頬送達のための組成物及び方法
Document Type and Number:
Japanese Patent JPH11513983
Kind Code:
A
Abstract:
A composition for transmucosally administering a drug to the oral cavity comprises an adhesive layer comprising a hydrophilic polymer having one surface adapted to contact a first tissue of the oral cavity and adhere thereto when wet and an opposing surface in contact with and adhering to an adjacent drug-containing layer comprising an effective amount of a drug and optionally an effective amount of a permeation enhancer, wherein the drug-containing layer is adapted to contact and be in drug transfer relationship with a mucosal tissue of the oral cavity when the adhesive layer contacts and adheres to the first tissue. Preferred drugs include peptides, such as glucagon-like insulinotropic peptides. A method of transmucosally administering a drug to the oral cavity is also disclosed.
Inventors:
Charles Dee, Evert
Haver, Sonia Jay
Gutniak, Mark Kay
Haver, Sonia Jay
Gutniak, Mark Kay
Application Number:
JP51671497A
Publication Date:
November 30, 1999
Filing Date:
October 22, 1996
Export Citation:
Assignee:
Ceratech Incorporated
International Classes:
A61K9/70; A61K9/00; A61K31/00; A61K38/00; A61K38/095; A61K38/22; A61K38/23; A61K38/28; A61L15/00; A61P1/00; A61P1/02; A61K9/20; (IPC1-7): A61K9/70; A61L15/00; A61K38/28; A61K38/23; A61K38/22; A61K38/11; A61K38/00; A61K31/00; A61K9/70
Attorney, Agent or Firm:
Kazuo Shamoto (4 outside)