Title:
【発明の名称】フィブリノーゲン変換酵素ハイブリド
Document Type and Number:
Japanese Patent JP2001526027
Kind Code:
A
Abstract:
Provided is a fusion protein comprising: a first polypeptide chain comprising a fibrinogen-converting enzyme; and a second polypeptide chain comprising a first member of a binding pair, wherein the second polypeptide chain is linked to the first polypeptide chain (1) directly by bonds utilizing the N-terminal amino groups, the C-terminal carboxy groups, or side-chain functionalities, or (2) via a bifunctional linkage moiety linking said groups or functionalities.
Inventors:
Cederholm-Williams, Stewart A.
Application Number:
JP2000524411A
Publication Date:
December 18, 2001
Filing Date:
December 09, 1998
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C12N15/09; A61K38/48; A61K47/42; A61K47/48; A61P7/04; C07H21/02; C07H21/04; C07K19/00; C12N1/21; C12N9/48; C12N9/64; C12P21/02; (IPC1-7): C12N15/09; A61K38/48; A61K47/42; A61K47/48; A61P7/04; C07H21/02; C07H21/04; C07K19/00; C12N1/21; C12N9/48; C12P21/02
Attorney, Agent or Firm:
Takashi Ishida (4 others)