Title:
【発明の名称】細胞表面にFGFレセプターを坦持する幹細胞
Document Type and Number:
Japanese Patent JP2002523085
Kind Code:
A
Abstract:
A composition of substantially purified pluripotent stem cells are positive both for fibroblast growth factor receptor (FGFR) and a phenotype indicative of a primitive state, such as CD34<+>, CD34<->lin<->, Thy-1<+>, AC133<+> or c-kit<+>. The state of being an embryonic stem cell is also a phenotype indicative of a primitive state. This population may be further defined by the subpopulations thereof which have another marker thereon indicative of endothelial cells, such a TIE-1<+>, TEK<+>, CD31<+>, VE-Cadherin<+> or VEGFR<+> or indicative of stromal cells, such as STRO-1<+>.
Inventors:
E. Lynette Wilson
Patricia e burger
Patricia e burger
Application Number:
JP2000567670A
Publication Date:
July 30, 2002
Filing Date:
August 31, 1999
Export Citation:
Assignee:
New York University
International Classes:
A61K35/14; A61K35/28; A61K35/44; A61K38/22; A61K48/00; A61P7/00; A61P35/00; A61P41/00; A61P43/00; C12N5/074; C12N5/0775; C12N5/0789; A61K35/12; (IPC1-7): C12N5/06; A61K35/14; A61K35/28; A61K35/44; A61K38/22; A61K48/00; A61P7/00; A61P35/00; A61P41/00
Foreign References:
| WO1996006928A1 | 1996-03-07 | |||
| WO1997027286A1 | 1997-07-31 | |||
| WO1996031598A1 | 1996-10-10 | |||
| WO1998024892A1 | 1998-06-11 |
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)