Title:
Transplantable swelling bioabsorbable polymer
Document Type and Number:
Japanese Patent JP6078480
Kind Code:
B2
Abstract:
The present invention relates to a polymer obtained from the polymerization of: (i) at least one monomer of formula (I) (CH2═CR1)CO—K (1) wherein: —K represents O—Z or N H—Z, Z representing (CR2R3)m-CH3, (CH2—CH2—O)m-H, (CH2—CH2—O)m-CH3, (CH2)m-NR4R5 with m representing an integer from 1 to 30; —R1, R2, R3, R4 and R5 independently represent H or a C1-C6 alkyl; (ii) at least between 0.1 and 50% mol, advantageously between 1 and 30% mol, more advantageously between 1 and 20 mol % of a cyclic monomer having a exomethylene group of formula (II) wherein: — R6, R7, R8 and R9 represent independently H or a C5-C7 aryl group or R6 and R9 are absent and R7 and R8 form together with the carbon atom on which they are bonded a C5-C7 aryl group; —i and j represent independently an integer chosen between 0 and 2; —X represents either O or X is not present and in this latter case, CR6R7 and CR8R9 are linked via a single bond C—C and (iii) at least one bio-resorbable block copolymer cross-linker.
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Inventors:
Moanne, Laurence
Laurent, Alexandre
Vasef, Michelle
Bedue, Laurent
Ruge, Stephanie
Bere, Valentin
Service, Emmeline
Laurent, Alexandre
Vasef, Michelle
Bedue, Laurent
Ruge, Stephanie
Bere, Valentin
Service, Emmeline
Application Number:
JP2013557126A
Publication Date:
February 08, 2017
Filing Date:
March 09, 2012
Export Citation:
Assignee:
Occar gel
Center Nacional de la Rushche Santi Fique (Seienères)
ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS
Universites Paris Didero Paris 7
Center Nacional de la Rushche Santi Fique (Seienères)
ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS
Universites Paris Didero Paris 7
International Classes:
C08F290/06; A61K9/00; A61K9/06; A61K9/14; A61K9/51; A61K31/05; A61K31/165; A61K31/167; A61K31/192; A61K31/196; A61K31/198; A61K31/245; A61K31/37; A61K31/404; A61K31/405; A61K31/407; A61K31/43; A61K31/445; A61K31/4745; A61K31/513; A61K31/519; A61K31/573; A61K31/7036; A61K31/704; A61K31/7068; A61K33/24; A61K47/32; A61K47/50; A61L27/14; A61P9/00; A61P11/02; A61P17/00; A61P17/02; A61P17/16; A61P23/02; A61P25/00; A61P29/00; A61P31/04; A61P35/00; C08F220/28
Domestic Patent References:
| JP2007112754A | ||||
| JP2009508991A | ||||
| JP2010518980A | ||||
| JP10174711A | ||||
| JP2001510151A | ||||
| JP2006232890A |
Foreign References:
| WO2010007564A1 |
Other References:
ANNA GALPERIN,Biomacromolecules,2010年,11,2583-2592
Attorney, Agent or Firm:
Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki
Junzo Koike
Hirofumi Toma
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki
Junzo Koike
Hirofumi Toma