Title:
Non-embedded chimeric lentivirus genome as an innovative vaccine against HIV-1
Document Type and Number:
Japanese Patent JP6324892
Kind Code:
B2
Abstract:
Novel nucleic acids include non-integrative chimeric retroviral genomes including the 5′ and 3′ long terminal repeat sequences (LTRs) of the caprine lentivirus: the Caprine Arthritis Encephalitis Virus (CAEV) or of another retrovirus not integrating human cells and at least one viral gene of another retrovirus. A vector including such a nucleic acid, an immunogenic or vaccinal composition including the vector or the nucleic acid, as well as their use for treating and/or preventing an infection by a retrovirus or a disease induced by a pathogenic agent are also described.
Inventors:
Jaia Schbrunn
Delphine Ardouber
Geraldine Aroad-The Blues
Delphine Ardouber
Geraldine Aroad-The Blues
Application Number:
JP2014530197A
Publication Date:
May 16, 2018
Filing Date:
September 12, 2012
Export Citation:
Assignee:
Center National de la Cherche Sientifique (Se en Els)
International Classes:
C12N15/09; A61K39/21; A61K48/00; A61P31/14; A61P31/18; A61P37/04
Domestic Patent References:
| JP2002513546A | ||||
| JP2007505923A |
Other References:
Virology,2007年,Vol. 364, No. 2,pp. 269-280
Retrovirology,2009年,Vol. 6, No. SUPPL. 2,P22
J. Virol.,2010年,Vol. 84, No. 3,pp. 1243-1253
AIDS Res. Hum. Retroviruses,1992年,Vol. 8, No. 3,pp. 403-409
Nucl. Acids Res.,1993年,Vol. 21, No. 15,pp. 3507-3511
Virology,2004年,Vol. 326, No. 1,pp. 47-56
Virology,2003年,Vol. 309, No. 1,pp. 41-52
Retrovirology,2009年,Vol. 6, No. SUPPL. 2,P22
J. Virol.,2010年,Vol. 84, No. 3,pp. 1243-1253
AIDS Res. Hum. Retroviruses,1992年,Vol. 8, No. 3,pp. 403-409
Nucl. Acids Res.,1993年,Vol. 21, No. 15,pp. 3507-3511
Virology,2004年,Vol. 326, No. 1,pp. 47-56
Virology,2003年,Vol. 309, No. 1,pp. 41-52
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro