Title:
ACETYLCHOLINE RECEPTOR INHIBITORY PEPTIDES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/138948
Kind Code:
A9
Abstract:
The present invention relates to acetylcholine receptor inhibitory peptides and uses thereof, wherein phages with high binding affinity for acetylcholine receptors were screened using a random peptide recombinant phage, and acetylcholine receptor-binding peptides were selected through DNA of the phages. By having confirmed, using the selected peptides, the binding affinity for acetylcholine receptors and the effect of inhibiting the action of acetylcholine receptors, and having confirmed, via the modifications of the peptides, peptide sites and sequences that are vital in binding to acetylcholine receptors, the acetylcholine receptor inhibitory peptides of the present invention are expected to be used in the development of a cosmetic composition for alleviating wrinkles, a medicine for the prevention or treatment of acetylcholine receptor-associated diseases, and a health functional food for the amelioration thereof.
Inventors:
KIM SUNG HYUN (KR)
CHOI WON IL (KR)
SHIN YONG CHUL (KR)
YUN YOUNG SUNG (KR)
KIM JIN HWA (KR)
LEE JEUNG HOON (KR)
CHOI WON IL (KR)
SHIN YONG CHUL (KR)
YUN YOUNG SUNG (KR)
KIM JIN HWA (KR)
LEE JEUNG HOON (KR)
Application Number:
PCT/KR2019/018460
Publication Date:
September 17, 2020
Filing Date:
December 26, 2019
Export Citation:
Assignee:
AMICOGEN INC (KR)
International Classes:
C07K7/06; A23L33/18; A61K8/64; A61K38/00; A61P25/14; A61Q19/00
Attorney, Agent or Firm:
GHONG-GAN INTERNATIONAL PATENT LAW FIRM (KR)
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