Title:
ANTHOZOA DERIVED CHROMO/FLUOROPROTEINS AND METHODS FOR USING THE SAME
Document Type and Number:
WIPO Patent Application WO2001027150
Kind Code:
A3
Abstract:
Anthozoa derived chromo/fluoroproteins and mutants thereof, as well as nucleic acid compositions encoding the same, are provided. Specific proteins of interest include chromo/fluoroproteins from the following specific anthozoa species: Anemonia majano, Clavularia sp., Zoanthus sp., Zoanthus sp., Discosoma striata, Discosoma sp. "red", Anemonia sulcata, Discosoma sp. "green", Discosoma sp. "magenta", and mutants thereof. Also provided are fragments of the subject proteins and nucleic acids encoding the same, as well as antibodies to the subject proteins and transgenic cells and organisms. The subject protein and nucleic acid compositions find use in a variety of different applications. Finally, kits for use in such applications that include the subject proteins are provided.
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Inventors:
LUKYANOV SERGEY ANATOLIEVICH (RU)
FRADKOV ARCADY FEDOROVICH (RU)
LABAS YULII ALEKSANDROVICH (RU)
MATZ MIKHAIL VLADIMIROVICH (RU)
TERSKIKH ALEXEY (US)
FRADKOV ARCADY FEDOROVICH (RU)
LABAS YULII ALEKSANDROVICH (RU)
MATZ MIKHAIL VLADIMIROVICH (RU)
TERSKIKH ALEXEY (US)
Application Number:
PCT/US2000/028477
Publication Date:
December 06, 2001
Filing Date:
October 13, 2000
Export Citation:
Assignee:
CLONTECH LAB INC (US)
LUKYANOV SERGEY ANATOLIEVICH (RU)
FRADKOV ARCADY FEDOROVICH (RU)
LABAS YULII ALEKSANDROVICH (RU)
MATZ MIKHAIL VLADIMIROVICH (RU)
TERSKIKH ALEXEY (US)
LUKYANOV SERGEY ANATOLIEVICH (RU)
FRADKOV ARCADY FEDOROVICH (RU)
LABAS YULII ALEKSANDROVICH (RU)
MATZ MIKHAIL VLADIMIROVICH (RU)
TERSKIKH ALEXEY (US)
International Classes:
A01K67/027; C07K14/435; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/65; C12P21/02; C12P21/08; (IPC1-7): C12N15/12; C07K14/435; C07K16/18; C12N15/62; C12N15/63; C12Q1/25
Domestic Patent References:
| WO1999049019A2 | 1999-09-30 |
Foreign References:
| DE19718640A1 | 1999-07-22 |
Other References:
WARD W W ET AL: "AN ENERGY TRANSFER PROTEIN IN COELENTERATE BIOLUMINESCENCE CHARACTERIZATION OF THE RENILLA GREEN-FLUORESCENT PROTEIN", JOURNAL OF BIOLOGICAL CHEMISTRY. (MICROFILMS),US,AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, vol. 254, no. 3, 10 February 1979 (1979-02-10), pages 781 - 788, XP002030243
DOVE SOPHIE G ET AL: "Isolation and partial characterization of the pink and blue pigments of pocilloporid and acroporid corals.", BIOLOGICAL BULLETIN (WOODS HOLE), vol. 189, no. 3, 1995, pages 288 - 297, XP000974081, ISSN: 0006-3185
TSIEN R Y: "THE GREEN FLUORESCENT PROTEIN", ANNUAL REVIEW OF BIOCHEMISTRY,PALTO ALTO, CA,US, vol. 67, 1998, pages 509 - 544, XP000946725
TSIEN R.Y.: "ROSY DAWN FOR FLUORESCENT PROTEINS", NATURE BIOTECHNOLOGY, vol. 17, no. 10, October 1999 (1999-10-01), pages 956 - 957, XP002159040
MATZ M V ET AL: "FLUORESCENT PROTEINS FROM NONBIOLUMINESCENT ANTHOZOA SPECIES", NATURE BIOTECHNOLOGY,NATURE PUBLISHING,US, vol. 17, no. 10, 1999, pages 969 - 973, XP000882891, ISSN: 1087-0156
See also references of EP 1305412A2
DOVE SOPHIE G ET AL: "Isolation and partial characterization of the pink and blue pigments of pocilloporid and acroporid corals.", BIOLOGICAL BULLETIN (WOODS HOLE), vol. 189, no. 3, 1995, pages 288 - 297, XP000974081, ISSN: 0006-3185
TSIEN R Y: "THE GREEN FLUORESCENT PROTEIN", ANNUAL REVIEW OF BIOCHEMISTRY,PALTO ALTO, CA,US, vol. 67, 1998, pages 509 - 544, XP000946725
TSIEN R.Y.: "ROSY DAWN FOR FLUORESCENT PROTEINS", NATURE BIOTECHNOLOGY, vol. 17, no. 10, October 1999 (1999-10-01), pages 956 - 957, XP002159040
MATZ M V ET AL: "FLUORESCENT PROTEINS FROM NONBIOLUMINESCENT ANTHOZOA SPECIES", NATURE BIOTECHNOLOGY,NATURE PUBLISHING,US, vol. 17, no. 10, 1999, pages 969 - 973, XP000882891, ISSN: 1087-0156
See also references of EP 1305412A2
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