Title:
ANTIMICROBIAL PEPTIDE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2006/088010
Kind Code:
A1
Abstract:
An antimicrobial peptide provided by the invention is an artificially designed antimicrobial peptide which does not exist in nature. Several antimicrobial peptides have a partial amino acid sequence of an &agr -domain contained in a human-derived VHL protein as an amino acid sequence involved in the expression of an antimicrobial property. Other several antimicrobial peptides have a partial amino acid sequence of a SOCS box motif contained in a certain SOCS box protein.
More Like This:
| WO/2019/138235 | ANIONIC NANOCOMPLEXES FOR NUCLEIC ACID DELIVERY |
| WO2002081498 | NOVEL PROTEINS AND NUCLEIC ACIDS ENCODING SAME |
| JP4590152 | Treatment of asthma |
Inventors:
YOSHIDA TETSUHIKO (JP)
KOBAYASHI NAHOKO (JP)
KOBAYASHI NAHOKO (JP)
Application Number:
PCT/JP2006/302508
Publication Date:
August 24, 2006
Filing Date:
February 14, 2006
Export Citation:
Assignee:
TOAGOSEI CO LTD (JP)
YOSHIDA TETSUHIKO (JP)
KOBAYASHI NAHOKO (JP)
YOSHIDA TETSUHIKO (JP)
KOBAYASHI NAHOKO (JP)
International Classes:
A61K38/00; A61K31/7088; A61K48/00; A61P31/04; C07K7/08; C12N15/09
Domestic Patent References:
| WO2002002055A2 | 2002-01-10 | |||
| WO2003091429A1 | 2003-11-06 | |||
| WO1998051794A1 | 1998-11-19 | |||
| WO1999026971A1 | 1999-06-03 | |||
| WO2000009553A2 | 2000-02-24 | |||
| WO2000059527A1 | 2000-10-12 | |||
| WO2001009175A2 | 2001-02-08 | |||
| WO2003091429A1 | 2003-11-06 |
Foreign References:
| JP2000063400A | 2000-02-29 | |||
| JP2001186887A | 2001-07-10 |
Other References:
BUTUYAN M.V. ET AL.: "Solution Structure and Dynamics of Yeast Elongin C in Complex with a von Hippel-Lindau Peptide", JOURNAL OF MOLECULAR BIOLOGY, vol. 312, 2001, pages 177 - 186, XP004466128
KAMURA T. ET AL.: "VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases", GENES & DEVELOPMENT, vol. 18, no. 24, 15 December 2004 (2004-12-15), pages 3055 - 3065, XP003000935
KAMIZONO S. ET AL.: "The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 16, 2001, pages 12530 - 12538, XP002240718
C. E. STEBBINS; W.G. KAELIN JR.; N. P. PAVLETICH, SCIENCE, vol. 284, 1999, pages 455 - 461
M. OHH; Y. TAKAGI; T. ASO; C. E. STEBBINS; N. P. PAVLETICH; B. ZBAR; R. C. CONAWAY; J. W. CONAWAY; W. G. KAELIN JR., THE JOURNAL OF CLINICAL INVESTIGATION, vol. 104, 1999, pages 1583 - 1591
T. KAMURA; S. SATO; D. HAQUE; L. LIU; W. G. KAELIN JR.; R. C. CONAWAY; J. W. CONAWAY, GENES & DEVELOPMENT, vol. 12, 1998, pages 3872 - 3881
D. J. HILTON; R. T. RICHARDSON; W. S. ALEXANDER; E. M. VINEY; T. A. WILLSON; N. S. SPRIGG; R. STARR; S. E. NICHOLSON; D. METCALF;, PNAS, vol. 95, 1998, pages 114 - 119
SHIMIZU ET AL., NATURE BIOTECHNOLOGY, vol. 19, 2001, pages 751 - 755
MADIN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 97, no. 2, 2000, pages 559 - 564
"Comprehensive Medicinal Chemistry", 1990, PERGAMON PRESS
See also references of EP 1849474A4
KAMURA T. ET AL.: "VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases", GENES & DEVELOPMENT, vol. 18, no. 24, 15 December 2004 (2004-12-15), pages 3055 - 3065, XP003000935
KAMIZONO S. ET AL.: "The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 16, 2001, pages 12530 - 12538, XP002240718
C. E. STEBBINS; W.G. KAELIN JR.; N. P. PAVLETICH, SCIENCE, vol. 284, 1999, pages 455 - 461
M. OHH; Y. TAKAGI; T. ASO; C. E. STEBBINS; N. P. PAVLETICH; B. ZBAR; R. C. CONAWAY; J. W. CONAWAY; W. G. KAELIN JR., THE JOURNAL OF CLINICAL INVESTIGATION, vol. 104, 1999, pages 1583 - 1591
T. KAMURA; S. SATO; D. HAQUE; L. LIU; W. G. KAELIN JR.; R. C. CONAWAY; J. W. CONAWAY, GENES & DEVELOPMENT, vol. 12, 1998, pages 3872 - 3881
D. J. HILTON; R. T. RICHARDSON; W. S. ALEXANDER; E. M. VINEY; T. A. WILLSON; N. S. SPRIGG; R. STARR; S. E. NICHOLSON; D. METCALF;, PNAS, vol. 95, 1998, pages 114 - 119
SHIMIZU ET AL., NATURE BIOTECHNOLOGY, vol. 19, 2001, pages 751 - 755
MADIN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 97, no. 2, 2000, pages 559 - 564
"Comprehensive Medicinal Chemistry", 1990, PERGAMON PRESS
See also references of EP 1849474A4
Attorney, Agent or Firm:
Abe, Makoto (Shirakawa Dairoku Bldg. 7th Fl. 2-18-5,
Nishiki, Naka-k, Nagoya-shi Aichi 03, JP)
Download PDF: