Title:
AUTOMATIC ANALYSIS OF CELLULAR SAMPLES
Document Type and Number:
WIPO Patent Application WO2005047896
Kind Code:
A3
Abstract:
The inventive method for automatically analysing a cellular sample consists (a) in colouring the cell nucleuses of a sample, (b) in obtaining at least one digital picture of the sample, and (c) in digitally analysing said image and is characterised in that the cell nucleus colouring stage (2) is embodied in the form of a DNA-non-specific colouring. In order to use the inventive method, said invention also relates to a method for selecting a culture medium, a method for measuring substance toxicity and to a method for measuring the cytopathological characteristics of a virus. A method for selecting pharmacological substances for treating excess weight and obesity diseases and a method for selecting substances for treating osteoporosis are also disclosed.
Inventors:
PINSET CHRISTIAN (FR)
Application Number:
PCT/FR2004/002854
Publication Date:
July 28, 2005
Filing Date:
November 05, 2004
Export Citation:
Assignee:
CELOGOS (FR)
PINSET CHRISTIAN (FR)
PINSET CHRISTIAN (FR)
International Classes:
G01N33/50; G01N33/569; G01N33/68; (IPC1-7): G01N33/50; G01N33/569; G01N33/68
Domestic Patent References:
| WO2002067195A2 | 2002-08-29 | |||
| WO1998038490A1 | 1998-09-03 |
Foreign References:
| EP1148330A2 | 2001-10-24 |
Other References:
KUO HON-REEN ET AL: "Identification of early apoptosis in Feulgen-stained cultured cells in situ by computerized image analysis", CYTOMETRY, vol. 33, no. 4, 1 December 1998 (1998-12-01), pages 420 - 427, XP002285587, ISSN: 0196-4763
MALPICA N ET AL: "APPLYING WATERSHED ALGORITHMS TO THE SEGMENTATION OF CLUSTERED NUCLEI", CYTOMETRY, ALAN LISS, NEW YORK, US, vol. 28, no. 4, 1997, pages 289 - 297, XP001149070, ISSN: 0196-4763
MALPICA N ET AL: "APPLYING WATERSHED ALGORITHMS TO THE SEGMENTATION OF CLUSTERED NUCLEI", CYTOMETRY, ALAN LISS, NEW YORK, US, vol. 28, no. 4, 1997, pages 289 - 297, XP001149070, ISSN: 0196-4763
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