Title:
BENZYLETHER AND BENZYLAMINO BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
Document Type and Number:
WIPO Patent Application WO2005032471
Kind Code:
A3
Abstract:
The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
Inventors:
NANTERMET PHILIPPE G (US)
RAJAPAKSE HEMAKA ANTHONY (US)
SELNICK HAROLD G (US)
RAJAPAKSE HEMAKA ANTHONY (US)
SELNICK HAROLD G (US)
Application Number:
PCT/US2004/032009
Publication Date:
July 07, 2005
Filing Date:
September 29, 2004
Export Citation:
Assignee:
MERCK & CO INC (US)
NANTERMET PHILIPPE G (US)
RAJAPAKSE HEMAKA ANTHONY (US)
SELNICK HAROLD G (US)
NANTERMET PHILIPPE G (US)
RAJAPAKSE HEMAKA ANTHONY (US)
SELNICK HAROLD G (US)
International Classes:
A61K31/195; C07C255/57; C07C311/08; C07D207/06; C07D207/08; C07D213/76; C07D213/81; C07D295/192; C07D333/20; C07D405/04; A61K; (IPC1-7): A61K31/195
Foreign References:
| US6869590B2 | 2005-03-22 | |||
| US6509335B1 | 2003-01-21 |
Other References:
See also references of EP 1673078A4
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