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Title:
CARBOHYDRATE-MODIFYING ENZYMES
Document Type and Number:
WIPO Patent Application WO2000063351
Kind Code:
A3
Abstract:
The invention provides human carbohydrate-modifying enzymes (CME) and polynucleotides which identify and encode CME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CME.

Inventors:
LAL PREETI (US)
YUE HENRY (US)
TANG Y TOM (US)
HILLMAN JENNIFER L (US)
BAUGHN MARIAH R (US)
YANG JUNMING (US)
Application Number:
PCT/US2000/010882
Publication Date:
August 09, 2001
Filing Date:
April 20, 2000
Export Citation:
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Assignee:
INCYTE GENOMICS INC (US)
LAL PREETI (US)
YUE HENRY (US)
TANG Y TOM (US)
HILLMAN JENNIFER L (US)
BAUGHN MARIAH R (US)
YANG JUNMING (US)
International Classes:
G01N33/50; A61K38/00; A61K38/43; A61K45/00; A61P3/10; A61P29/00; A61P35/00; A61P37/02; C07K16/40; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/10; C12N9/12; C12N9/24; C12N15/09; C12Q1/68; G01N33/15; G01N33/53; G01N33/566; G01N33/68; (IPC1-7): C12N9/00; C12N15/00
Domestic Patent References:
WO1994025061A11994-11-10
WO1990007573A11990-07-12
WO1994014472A11994-07-07
WO1994023070A11994-10-13
Foreign References:
EP0893506A11999-01-27
EP0737745A11996-10-16
Other References:
MÜNSTER ANJA-K ET AL: "Mammalian cytidine 5'-monophosphate N-acetylneuraminic acid synthetase: A nuclear protein with evolutionarily conserved structural motifs.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 95, no. 16, 4 August 1998 (1998-08-04), pages 9140 - 9145, XP002153786, ISSN: 0027-8424
NEHES V L ET AL: "HUMAN LYSOSOMAL ALPHA-MANNOSIDASE: ISOLATION AND NUCLEOTIDE SEQUENCE OF THE FULL-LENGTH CDNA1", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,US,ACADEMIC PRESS INC. ORLANDO, FL, vol. 200, no. 1, 15 April 1994 (1994-04-15), pages 239 - 245, XP000647751, ISSN: 0006-291X
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