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Title:
CHEMOKINE RECEPTOR
Document Type and Number:
WIPO Patent Application WO2001027146
Kind Code:
A3
Abstract:
The invention provides polypeptides and polynucleotides encoding a novel chemokine receptor, CCX CKR. The invention further provides reagents and methods for identifying agents that modulate the activity or expression of the receptors, as well as methods for detecting receptor expression.

Inventors:
GOSLING JENNIFA (US)
DAIRAGHI DANIEL J (US)
HANLEY MICHAEL (US)
MIAO ZHENHUA (US)
TALBOT DALE (US)
SCHALL THOMAS J (US)
Application Number:
PCT/US2000/028067
Publication Date:
November 22, 2001
Filing Date:
October 10, 2000
Export Citation:
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Assignee:
CHEMOCENTRYX INC (US)
GOSLING JENNIFA (US)
DAIRAGHI DANIEL J (US)
HANLEY MICHAEL (US)
MIAO ZHENHUA (US)
TALBOT DALE (US)
SCHALL THOMAS J (US)
International Classes:
A61K45/00; A61P29/00; A61P31/00; A61P35/00; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07K14/52; C07K14/715; C07K16/28; C07K19/00; C12N1/15; C12N1/19; C12N5/10; C12N15/02; C12N15/09; C12P21/02; C12P21/08; C12Q1/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/531; G01N33/566; G01N33/577; G01N33/68; (IPC1-7): C07K14/705; C07K14/47
Domestic Patent References:
WO1999024463A21999-05-20
WO2000026369A12000-05-11
WO1999052945A21999-10-21
WO2000064941A22000-11-02
Foreign References:
EP0899332A21999-03-03
Other References:
DATABASE EMBL 1 October 2000 (2000-10-01), SCHWEICKART V. L. ET AL., GOSLING J. ET AL. AND KHOJA H. ET AL.: "CCR11 or CCBP" or VSHK1", XP002163536
DATABASE EMBL 14 October 1999 (1999-10-14), ASAHI KASEI KOGYO KK: "new seven-pass transmembrane receptor protein ...", XP002163537
MATSUOKA ET AL: "Identification of novel members of G-protein coupled receptor subfamily", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,US,ACADEMIC PRESS INC. ORLANDO, FL, vol. 194, no. 1, 15 July 1993 (1993-07-15), pages 504 - 511, XP002102959, ISSN: 0006-291X
O'DOWD ET AL: "A novel gene for a putative G-protein-coupled receptor with an abundant expression in brain", FEBS LETTERS,ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM,NL, vol. 394, 1996, pages 325 - 329, XP002102960, ISSN: 0014-5793
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