Title:
COMPOSITION FOR PREVENTING OR TREATING CHRONIC OR ACUTE VIRUS INFECTION AND/OR SEPSIS IN HUMANS OR ANIMALS
Document Type and Number:
WIPO Patent Application WO/2021/198940
Kind Code:
A1
Abstract:
Provided is a composition or medicine for treating Covid-19, and a medicine for treating chronic or acute virus infection and/or sepsis mainly in humans, said medicine indicating a superior antiviral effect to the antiviral effect of conventionally known DMSO or I2. This composition for preventing or treating chronic or acute virus infection and/or sepsis in humans or animals contains at least one iodine source selected from the group consisting of iodide salts and povidone-iodine, and at least one sulfur source selected from the group consisting of dimethyl sulfoxide and methylsulfonylmethane.
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Inventors:
HOANG XUAN BA (VN)
HAN BO (VN)
NGUYEN QUANG THAI (VN)
HAN BO (VN)
NGUYEN QUANG THAI (VN)
Application Number:
PCT/IB2021/052677
Publication Date:
October 07, 2021
Filing Date:
March 31, 2021
Export Citation:
Assignee:
THAI MINH PHARMACEUTICALS JSC (VN)
International Classes:
A61K33/18; A61K9/08; A61K9/12; A61K31/10; A61K31/79; A61P31/12; A61P31/14; A61P43/00
Domestic Patent References:
| WO2019009630A1 | 2019-01-10 |
Foreign References:
| JP2018506577A | 2018-03-08 | |||
| JP2018070583A | 2018-05-10 | |||
| JP2019038795A | 2019-03-14 | |||
| JP2015507008A | 2015-03-05 | |||
| JP2004352642A | 2004-12-16 |
Other References:
READ SCOTT A, OBEID STEPHANIE, AHLENSTIEL CHANTELLE, AHLENSTIEL GOLO: "The role of zinc in antiviral immunity", ADVANCES IN NUTRITION, vol. 10, no. 4, 2019, pages 696 - 710, XP055927657
HUANG SHING-HWA, WU CHIH-HSIUNG, CHEN SHYI-JOU, SYTWU HUEY-KANG, LIN GU-JIUN: "Immunomodulatory effects and potential clinical applications of dimethyl sulfoxide", IMMUNOBIOLOGY, vol. 225, no. 151906, 22 January 2020 (2020-01-22), pages 1 - 6, XP086168972
BIDRA AVINASH S., PELLETIER JESSE S, WESTOVER JONNA B, FRANK SAMANTHA, BROWN SETH M, TESSEMA BELACHEW: "Rapid in-vitro inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using povidone-iodine oral antiseptic rinse", JOURNAL OF PROSTHODONTICS, vol. 29, no. 6, 16 June 2020 (2020-06-16), pages 529 - 533, XP055927662
KHAN M.M. ET AL.: "Repurposing 0.5% povidone iodine solution in otorhinolaryngology practice in Covid 19 pandemic", AM.J.OTOLARYNGOL., vol. 41, no. 102618, 18 June 2020 (2020-06-18), pages 1 - 5, XP055927670
HOANG BA X, HOANG HUY Q, HAN BO: "Zinc iodide in combination with dimethyl sulfoxide for treatment of SARS-CoV-2 and other viral infections", MEDICAL HYPOTHESES, vol. 143, no. 109866, October 2020 (2020-10-01), pages 1 - 54, XP086271865
HUANG SHING-HWA, WU CHIH-HSIUNG, CHEN SHYI-JOU, SYTWU HUEY-KANG, LIN GU-JIUN: "Immunomodulatory effects and potential clinical applications of dimethyl sulfoxide", IMMUNOBIOLOGY, vol. 225, no. 151906, 22 January 2020 (2020-01-22), pages 1 - 6, XP086168972
BIDRA AVINASH S., PELLETIER JESSE S, WESTOVER JONNA B, FRANK SAMANTHA, BROWN SETH M, TESSEMA BELACHEW: "Rapid in-vitro inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using povidone-iodine oral antiseptic rinse", JOURNAL OF PROSTHODONTICS, vol. 29, no. 6, 16 June 2020 (2020-06-16), pages 529 - 533, XP055927662
KHAN M.M. ET AL.: "Repurposing 0.5% povidone iodine solution in otorhinolaryngology practice in Covid 19 pandemic", AM.J.OTOLARYNGOL., vol. 41, no. 102618, 18 June 2020 (2020-06-18), pages 1 - 5, XP055927670
HOANG BA X, HOANG HUY Q, HAN BO: "Zinc iodide in combination with dimethyl sulfoxide for treatment of SARS-CoV-2 and other viral infections", MEDICAL HYPOTHESES, vol. 143, no. 109866, October 2020 (2020-10-01), pages 1 - 54, XP086271865
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